Associate Scientist

2 days ago

Hillsboro, United States Compass Consulting Full time

About the Company: Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.



About the Role: RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures. We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production at the Company and help advance our portfolio.



Responsibilities:



  • Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support pipeline productions adhering to established protocols.
  • Maintain seed train cell cultures in bioreactors and shake flasks.
  • Operate liquid handlers - Tecan and Hamilton for automated processes.
  • Operate wave bag reactors for productions and cell maintenance.
  • Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex, Cedex and bioreactors.
  • Participate in troubleshooting production or platform processes.
  • Participate in lab management and data management.
  • Contribute to improving existing cell culture platforms and developing new platforms to deliver diverse protein and cellular reagents to enable a large number of research programs.
  • The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback.
  • The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner.
  • They should be able to work independently within guidelines and policies, with minimal guidance.


Qualifications:



  • PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields.
  • Suspension adapted mammalian cell culture (CHO and/or HEK293).
  • Excellent written and verbal communication skills, and have strong collaborative skills.


Preferred Skills:



  • State-of-the-art transient and stable protein expression experience.
  • Relevant bioreactor experience.
  • Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star.
  • Knowledge of cell biology, cell engineering, molecular biology, recombinant protein purification and protein characterization is preferred.


Pay range and compensation package: Pay range or salary or compensation.



Equal Opportunity Statement: Include a statement on commitment to diversity and inclusivity.

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