Research Associate, Analytical Development

2 weeks ago


Woburn, United States Planet Pharma Full time

606946


Our client, a leading Pharmaceutical company in Woburn, MA, is looking for a Research Associate, Analytical Development to perform analytical chemistry and biophysical methods for the testing of AAV gene therapy products, to support process development and product characterizations.


Required Skills:

  • BS or MS in Biophysics, Biochemistry, Analytical Chemistry or a related discipline with relevant lab experience.
  • 1-2 years of industry experience
  • HPLC/UPLC experience analyzing nucleic acids, virus capsids, antibodies and/or other biologics materials by a variety of chromatographic methods (RP, SEC, IEX, SEC/FFF-MALS)
  • Experience with SV-AUC analyzing Viral vectors or proteins is preferred.
  • Experience with CE-SDS and cIEF, for the analysis of biological materials is desired.
  • Working experience in viral particle analysis is highly desired.


Responsibilities:

  • Perform UV, HPLC, SV-AUC and CE-based methods to quantitatively measure the purity of the AAV gene therapy vectors and support process development.
  • Assess and implement new analytical platforms, such as DLS, SEC-MALS, etc., to determine AAV capsid identity, quality, and quantity.
  • Investigate and evaluate cutting edge biophysical and analytical instrumentation.
  • Write, prepare and present technical data, technical reports and standard operating procedures (SOPs) for internal use and transfer to external sites.
  • Provide technical support to cross-function groups and external collaborators.



***Compensation within this range will be commensurate with level of experience***



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