Research Associate, Analytical Development
2 weeks ago
606946
Our client, a leading Pharmaceutical company in Woburn, MA, is looking for a Research Associate, Analytical Development to perform analytical chemistry and biophysical methods for the testing of AAV gene therapy products, to support process development and product characterizations.
Required Skills:
- BS or MS in Biophysics, Biochemistry, Analytical Chemistry or a related discipline with relevant lab experience.
- 1-2 years of industry experience
- HPLC/UPLC experience analyzing nucleic acids, virus capsids, antibodies and/or other biologics materials by a variety of chromatographic methods (RP, SEC, IEX, SEC/FFF-MALS)
- Experience with SV-AUC analyzing Viral vectors or proteins is preferred.
- Experience with CE-SDS and cIEF, for the analysis of biological materials is desired.
- Working experience in viral particle analysis is highly desired.
Responsibilities:
- Perform UV, HPLC, SV-AUC and CE-based methods to quantitatively measure the purity of the AAV gene therapy vectors and support process development.
- Assess and implement new analytical platforms, such as DLS, SEC-MALS, etc., to determine AAV capsid identity, quality, and quantity.
- Investigate and evaluate cutting edge biophysical and analytical instrumentation.
- Write, prepare and present technical data, technical reports and standard operating procedures (SOPs) for internal use and transfer to external sites.
- Provide technical support to cross-function groups and external collaborators.
***Compensation within this range will be commensurate with level of experience***
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