Research Associate

1 month ago

Princeton, United States Optimeos Life Sciences Full time

Who We Are

Optimeos Life Sciences is pioneering a transformative nanotechnology platform for non-viral gene therapies. We are a venture-backed, early-stage company, founded by experienced entrepreneurs and leading nanotechnology experts. We are developing and commercializing an innovative encapsulation technology developed at Princeton University. We are a close-knit and dynamic team with locations at Princeton Innovation Center BioLabs and uCity Square in Philadelphia. Optimeos is growing our team as we take on crucial unmet medical needs.


Summary of the Position

Research associates work with their functional area leads to carry out benchtop experiments that advance our non-viral gene therapies towards the clinic. You will develop and conduct in vitro and ex vivo assays characterizing novel nucleic acid formulations for potency, specificity, immunogenicity, and toxicity. In the course of your work, you will utilize standard biochemistry and molecular biology techniques such as cell isolation, ELISA, chromogenic and fluorogenic assays, flow cytometry, western blots, protein/RNA/DNA gels, bacterial culture, and mammalian cell culture. The successful applicant will be proficient in aseptic techniques and wet-lab basics. There will also be opportunities to support in vivo studies at our Philadelphia location based on aptitude and interest. At Optimeos, you will be in a dynamic environment with many opportunities to gain new skills as our needs evolve. You will gain first-hand experience with company creation and growth, pharmaceutical development, and the state-of-the-art in gene therapy.

·       Experience Level: BS/MS with 0-2 years relevant experience

·       Location: Princeton, NJ

·       Full-time

·       Competitive compensation and benefits


Responsibilities

·       Plan, conduct, and analyze wet-lab experiments in a safe and reproducible manner

·       Accurately document and convey experimental results in sub-team and full-team settings

·       Support gene therapy formulation screening through cell culture maintenance and functional assays (flow cytometry, biochemical assays, western blots, etc)

·       Assist with new method/assay development


Qualifications

·       BS/MS in biochemistry/molecular biology and related disciplines

·       0-2 years of industry experience

·       Applicants with 0 years of post-bac work experience need at least 1 year (or 2 summers) of wet-lab experience in aseptic technique through a university research lab or internship

·       Immunology experience preferred

·       Experience and familiarity with cell and gene therapies a plus

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