Associate Scientist, Analytical Development

2 weeks ago

South San Francisco, United States Allogene Therapeutics Full time
Job Description

About Allogene:

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T™) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visit www.allogene.com, and follow @AllogeneTx on X (formerly Twitter) and LinkedIn.

About the role:

We are seeking a highly motivated Associate Scientist to join our Analytical Development group and contribute to the commercialization of allogenic CAR T therapies. The Associate Scientist will play a key role in CAR T cell therapy related analytical assay development and execution of drug product release and characterization assay.

The individual will work closely with peers in assay development, assay qualification, execution of the release and characterization assays, comprehensive risk assessments, and data synthesis that allows for the subsequent analytical assay tech transfer. This role will be based at the headquarters in South San Francisco, CA.

Responsibilities include, but are not limited to:

Perform analytical assays such as PCR, ELISAs, cell-based potency assays and flow cytometry, etc., for cell therapy products. Maintain mammalian cell culture for testing. Maintain, calibrate, and operate analytical instruments. Maintain sample inventories. Ensure high-quality, timely documentation in electronic laboratory notebooks (ELN) with great attention to details. Coherently summarize and communicate experiments and findings and present study results at team meetings to internal stakeholders Assist in analytical method optimization, development, and qualification in support of product and process development and product characterization. Demonstrate strong accountability, organizational and interpersonal skills, and apply sound scientific and technical experience. Work collaboratively with cross-functional teams to meet deadline-dependent milestones and advance the development of Allogene’s CAR T programs. Other duties as assigned.

Position Requirements & Experience:

Bachelor’s Degree with 0-3 years of relevant cell biology, immunology or biochemistry experience. Ability to work independently and as part of a team. Experience with cell culture, cell banking, and aseptic technique is required. Prior working knowledge of nucleic acid isolation, quantification, and PCR is preferred. Prior working knowledge in ELISA, FACS a plus. Experience with data analysis tools such as Prism, FlowJo and Microsoft Excel a plus. Working knowledge of quality control and assay qualification is a plus. Self-motivated, organized and detail-orientated, with a positive “can-do” attitude towards assigned tasks is expected. Candidates must be authorized to work in the U.S.

We offer a chance to work with talented people in a collaborative environment. Actual pay will be determined based on experience, qualifications, geographic location, business needs, and other job-related factors permitted by law.

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