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Postdoc Fellow

4 months ago

Houston, United States MD Anderson Cancer Center Full time
The Immunology department at MD Anderson Cancer Center seeks to determine the fundamental cellular and molecular mechanisms of a wide range of processes by which the body recognizes and eliminates pathogens and uses these findings to unleash the patient's immune system against previously treatment-resistant cancers. Treating the immune system rather than the cancer itself, the therapeutics developed apply to many cancers. The role of immunological and epigenetic pathways in resistance and response to immune checkpoint therapy.

General Laboratory duties or procedures:

1. To work with animal and human samples (Handling, Treatments, Inoculation, and Processing of samples for long-term storage)

2. Perform single-cell RNA sequencing, able to run the data in different packages and analyze the tumor immune micro-environment

3. Perform ATAC-sequencing, able to run the data in different packages and analyze chromatin accessibility
4. CyTOF staining and analyses of the data

5. Flow cytometry staining and analyses

6. Perform CHIP-sequencing, able to run the data in different packages and analyze chromatin accessibility

7. Molecular biology techniques like PCR, RNA/DNA isolation, western blot and knock in/ out using CRISPR technology.

LEARNING OBJECTIVES
1. To understand immunological pathways involved in response and resistance to immune checkpoint therapy at single-cell level.
2. To understand the epigenetic regulations of immune sub-populations.
3. To analyze the single-cell RNA sequencing and ATAC sequencing data.

ELIGIBILITY REQUIREMENTS
PhD in Immunology, Biochemistry, or Molecular Biology

POSITION INFORMATION
MD Anderson follows the NIH stipend levels as outlined by the . This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience.

MD Anderson offers compensated trainees:
- Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week
- Group Dental, Vision, Life, AD&D and Disability coverage
- Paid Education Vacation and Sick Leave
- Paid institutional holidays, wellness leave, childcare leave and other paid leave programs
- Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans
- Employer paid life, AD&D and an illness-related reduced salary pay program
- Health Savings Account and Dependent Care Reimbursement flexible spending accounts
- Fertility benefits
- State of Texas longevity pay
- Extensive wellness, fitness, employee health programs and employee resource groups