Senior Scientific Lead, Large Molecule Biology
4 weeks ago
We’re looking for people who are determined to make life better for people around the world.
About
aims to create medicines that make life better for all those affected by cancer around the world. Bringing together the focus and spirit of a biotech with the scale, resources, and heritage of Lilly, our team is focused on rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating oncology medicines that unequivocally show early signs of clinical activity and will matter to patients. We intend to curate a balanced pipeline of medicines, either internally or externally discovered, with the potential to treat cancer with dramatic effect. was created in December 2019, combining the Lilly Oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. is a global organization with team members in Louisville, Colorado; Indianapolis, Indiana; New York City, New York; San Diego, California; South San Francisco, California; Stamford, Connecticut; and Madrid, Spain.
Position Summary:
You will collaborate with a dynamic group of scientists (internal team as well as external CROs) conducting various research projects to identify large molecule/biologics which can effectively treat various forms of cancer. This is a senior role with significant hands-on responsibilities where you will lead from the bench. You will design and perform experiments that determine the efficacy of pipeline agents through a variety of techniques such as in vitro and ex vivo assays, target validation, and functional screening. Collaboration across functional areas within is required including senior leadership. You will be a key member of the biologics organization, where you will be responsible for maintaining the scientific quality and efficiency of your organization, as well as assist and contribute to the strategic direction of large molecule discovery.
*Roles and Responsibilities of the Position:
Design and oversee the execution of key mechanistic and discovery biology experiments with ADCs or CD3 T-cell biologics
Maintain focus on project deliverables and prioritize experiments and efforts accordingly
Oversee/perform assays to identify the drug candidate and evaluate the candidate for clinical testing
Liaise with CROs and vendors to outsource activities, provide input to management team on vendor selection
Provide scientific expertise when determining organizations to strategically partner with
Interrogate experimental conduct of third parties/vendors
Participate in target identification in collaboration with leadership
Indirectly oversee work of third parties/vendors (e.g., CROs)
Manage resource allocation effectively
Build roadmaps to execute on specific targets, and overall strategic projects
*Required Qualifications:
PhD in cellular biology, immunology, or allied disciplines with minimum 3+ years’ industry experience OR BS/MS with 10+ years of direct pharmaceutical/biotechnology experience. Experience in leading a project (i.e., to IND, FHD and/or out licensing) highly preferredAdditional Preferences:
Experience writing reports and supporting documentation for regulatory filings preferred
Hands-on experience with in-vitro assay development for large molecules including ADCs and other modalities
Strong attention to detail and highly goal oriented with demonstrated critical thinking capabilities
Ability to trouble shoot effectively and think outside of the box
Ability to collaborate with translational biology functions (PK/PD, toxicology, Ab discovery)
Proven success leading, managing, and coaching others (either directly or indirectly)
Demonstrated ability and track record in managing work overseen by third parties/vendors/strategic partners
Demonstrated experience in working collaboratively across various scientific disciplines to meet end goals of business
Demonstrated excellence in making key strategic decisions in support of broader business goals
Excellent written and verbal communication skills
Physical Demands/ Travel:
The physical demands of this job are consistent with laboratory/bench setting
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position’s work environment is in a lab.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions
Lilly currently anticipates that the base salary for this position could range from between $143,250 to $210,100 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Of course, the compensation described above is subject to change and could be higher or lower than the range described above. Further, Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
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