Principal Scientist
Save this job and keep your search organized
Create a free account to save jobs, create alerts and return to this listing from your dashboard.
By continuing, you agree to our Terms & Privacy Policy.
Role
Principal Scientist in High-Content Imaging within Johnson & Johnson's Innovative Medicine division, focusing on advancing therapeutic discovery in Immunology, Neuroscience, and Oncology.
Responsibilities include developing, validating, and deploying complex high-content imaging assays across diverse cell models and tissues, establishing workflows, troubleshooting, and optimizing protocols. The role involves collaborating with internal teams, CROs, and external partners to generate high-quality data, support data analysis pipelines, and translate imaging readouts into biological insights.
Qualifications
Ph.D. in Biochemistry, Systems Biology, or related field; minimum of 4 years industry experience with proven expertise in high-content imaging, assay development, and computational image analysis; excellent communication and collaborative skills.
Preferred
Experience with complex cell/tissue models, external collaborations, data integration, and programming in R/Python; familiarity with AI/ML approaches is a plus.
High-value specifics include application across disease-relevant models in Immunology, Neuroscience, and Oncology, with a focus on drug discovery workflows. The position is based in Spring House, PA, with an emphasis on technical leadership and innovation in high-dimensional biological assays.
#J-18808-Ljbffr-
Principal Scientist, Discovery-Oncology
2 days ago
Spring House, PA, United States Johnson & Johnson Co. Full-time $180,000 - $240,000At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
Principal Scientist, Oncology Discovery
2 days ago
Spring House, PA, United States Johnson & Johnson Co. Full-time $180,000 - $240,000Johnson & Johnson Innovative Medicine Oncology Discovery is seeking 2 Principal Scientists to lead discovery programs in oncology from Spring House, PA. The roles require senior scientists to drive pharmacology and assay development for T-cell engagers and small molecules in solid tumors.Ideal candidates hold a PhD in Cancer Biology or Immunology with 6+...
-
Principal Scientist, Discovery-Oncology
4 days ago
Spring City, PA, United States Johnson and Johnson Full-timeAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
Principal Scientist, Agentic Cheminformatics
3 days ago
Spring House, PA, United States Johnson Johnson Full-timeJohnson & Johnson is recruiting a Principal Scientist, Scientific Workflows & Agentic Cheminformatics to join our In Silico Drug Discovery team. The position is based in Spring House, PA or Cambridge, MA with some travel; no remote option.This role focuses on leading design and validation of agent-enabled workflows to advance discovery across multiple use...
-
Principal Scientist, Discovery-Oncology
4 days ago
Spring House, PA, Montgomery County, PA; Pennsylvania, United States Johnson & Johnson Full-timeJohnson & Johnson seeks two Principal Scientists for oncology discovery in Spring House, Pennsylvania. The role involves leading scientific teams in developing pharmacology packages for T-cell engagers and small molecule therapeutics targeting prostate cancer, with emphasis on overcoming solid tumor microenvironment challenges. Responsibilities
-
Principal Scientist, Scientific Workflows
3 days ago
Spring House, PA, United States Johnson Johnson Full-timeAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
Principal Scientist, AI-Native Discovery
2 days ago
Spring House, PA, United States Johnson & Johnson Co. Full-time $117,000 - $201,000At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
Principal Scientist, Discovery-Oncology
5 days ago
Spring House, PA, United States J&J Family of Companies Full-timePrincipal Scientists, Oncology Discovery, Innovative Medicine At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative...
-
Principal Scientist, Discovery-Oncology
7 days ago
Spring House, Pennsylvania, United States of America, PA Johnson Johnson Full-timeAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to...
-
Principal Scientist, AI-Native Discovery
4 days ago
Spring House, PA, United States J&J Family of Companies Full-timeAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...