Post Doctoral Associate Chemical Biology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Position Overview
The Post Doctoral Protein Biochemistry Research Scientist will focus on peptide synthesis and oral macrocycle efforts at Protomer. This includes the application of synthetic approaches and display technologies to improve the current business and support generation of new molecules.

The position will provide technical and scientific support within a dynamic research and development processes (synthesis and purification) for biomolecules including proteins and peptides. The successful candidate will be responsible for designing and executing experiments to advance process knowledge, process optimization and production technical transfer, as needed. This position allows for development of a comprehensive understanding of the R&D process and the essential role scientists play in creating solutions for Protomer team within Eli Lilly and Company.

Key Objectives/Deliverables

• Understanding the scientific principles required for testing intermediates and drug substances and peptides.
• Identify and support the implementation of new technologies/methods that offer significant advantages in compound generation and speed.
• Streamline analytical strategies to reduce the overall testing burden in terms of cost and/or time.
• Provide support and lead peptide synthesis efforts including novel insulin generation and testing.
• Ensure the analytical control strategy from raw materials through drug substance is technically sound, cost effective, compliant, and sustainable.
• Troubleshoot and investigate major analytical issues.
• Participate in technology transfer as needed.

Basic Requirements

• Ph.D. in scientific fields of Chemical Engineering, Chemistry, Biochemistry, Biology, or related fields.
• Experience with LC-MS and/or MS/MS instrumentation

Addition Skills/Preferences

• Peptide synthesis with CEM or AAPPTEC systems or related systems
• Experience developing protein/peptide analytical chromatographic separations
• Strong statistical skills
• Familiarity with GC/MS
• Strong scientific communication skills
• Demonstrated record of scientific achievement
• Demonstrated problem solving abilities
• Ability to work well independently and collaboratively
• Understanding of protein, peptide chemistry and/or characterization.

This position is not permanent. It is for a fixed term position up to a maximum of 4 years.

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Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is

$58,000 - $100,320

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.