Senior Director, Supply Chain

When our people share why they joined Rapport and love it here, it comes down to three things: the science, the mission, and the team. At Rapport, we're driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we're doing this with extraordinary science and awesome people (affectionately called Rapptors).

Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials for neuropathic pain and bipolar disorder.

The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you're as excited about this opportunity as we are

Your Impact
As the Senior Director of Supply Chain, you will lead the end-to-end supply chain strategy and execution that drives the transition from clinical success to global commercialization

Your Day-to-Day

• Global Supply Chain Strategy & Execution: Develop and lead the global supply chain strategy to support Phase 3 clinical trials and commercial readiness, including demand forecasting, production planning, procurement, inventory management, and logistics.
• Clinical Supply Chain Leadership: Oversee global clinical supply planning and execution to ensure timely and compliant delivery of clinical trial materials.
• CMC Integration: Partner closely with CMC, Regulatory, Clinical Operations, and Quality teams to align supply chain operations with drug substance and drug product manufacturing campaigns, ensuring readiness for pivotal trials and regulatory submissions.
• Vendor & CDMO Management: Lead strategic sourcing and management of global CDMOs, packaging and labeling vendors, and logistics providers. Negotiate contracts, manage performance, and ensure adherence to quality and compliance standards.
• Cross-Functional Collaboration: Serve as a key partner to Clinical Operations, Regulatory Affairs, Quality Assurance, Finance, and New Product Planning functions to ensure integrated planning and execution across the development lifecycle.
• Operational Excellence & Risk Management: Implement robust supply chain systems, processes, and KPIs to drive efficiency, scalability, and transparency. Proactively identify and mitigate supply chain risks, including supply disruptions, regulatory changes, and geopolitical factors.
• Team Leadership & Organizational Development: Lead a high-performing global supply chain team. Foster a culture of accountability, innovation, and continuous improvement aligned with company values and growth objectives.

Must-Haves

• 15+ years of progressive experience in global supply chain management within the biopharmaceutical industry.
• Academic degree(s) in Management and/or Life Sciences preferred.
• Demonstrated success in leading supply chain operations through global Phase 3 clinical trials and preparing for commercial launch.
• Deep understanding of global regulatory requirements and clinical development processes for small molecule therapeutics.
• Proven track record of managing complex global supply networks and external manufacturing partners.
• Experience implementing supply chain systems and digital tools to support data-driven decision-making.
• Exceptional leadership, communication, and cross-functional collaboration skills.

What Makes Rapport Special

• Every role has meaning. We're determined to discover a better way for patients, and you'll feel the passion from the start.
• We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.
• Your perspective matters. Stick your neck out, share your ideas – we work as a team.
• We have FUN. We hire smart, dedicated, down-to-earth people that you'll enjoy spending time with.
• Leadership that CARES – about you, your growth + development.
• We're bicoastal. Whether you're in the lab full-time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.
• Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more
• You get to be YOU Show up as you are and make every day count.

Your Compensation
We get it. Compensation is an important part of your offer. You shouldn't be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this? We tell you about our hiring range now - we expect the hiring range for this role to be $250,000-$270,000. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package. We don't stop here - if you join Rapport, we go to the next level. We share our full salary ranges for every level across our company.

Hybrid Work Environment
We prioritize in person connection with our fellow Rapptors Our team members come together onsite at our Boston office on Tuesday and Wednesday. In January 2026, this will shift to three days a week to create more opportunities for innovation, collaboration, and connection.

Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

Note to Employment Agencies:
Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited.

CCPA disclosure notice can be found here.