Senior Scientist

6 days ago

Thousand Oaks, California, United States SPECTRAFORCE Full time

Job Title: Senior Scientist

Location: Thousand Oaks, CA; 91320

Duration: 2 years

Description:

Note:

Fully Onsite

Regular Working Hours

An ideal candidate has a PhD degree in organic chemistry or a related field (or Master's with 3 years experience) with experience in bioconjugation and/or antibody drug conjugate (ADC) development. The candidate will be proficient in standard organic characterization techniques (HPLC, LC-MS, NMR, Q-NMR) as well as familiarity with bioanalytical techniques used for bioconjugation reaction monitoring/characterization (e.g. CE-SDS, icIEF, soloVPE, etc.). The candidate will work as part of a drug development team with a range of responsibilities including: conjugation reaction development, characterization of reaction profiles and kinetics studies, impurity and residuals removal (e.g. ultrafiltration/diafiltration) and commercial process development activities. The candidate will maintain laboratory notebooks and computer files, participate in group and project meetings. The candidate will work in a team environment collaborating with various colleagues in process development including process chemists and analytical chemists.

Preferred Qualifications:


• PhD in organic chemistry or a related field:


• 2+ years of experience in the biopharmaceutical or pharmaceutical industry with experience in bioconjugation and/or ADCs


• Knowledge of bioconjugation/ADC processes and analysis


• Competent in analytical techniques including NMR, HPLC and Mass Spec


• Familiarity with techniques for analyzing bioconjugates (e.g. SEC, HIC, etc.)


• Experience in reviewing and interpreting analytical data


• Demonstrated ability to work in a fast-paced team environment


• Excellent presentation, written and verbal skills


• Knowledge of basic software including Microsoft Word, Excel, PowerPoint, and Outlook

Top 3 Must Have Skill Sets:

  • Bioconjugation or antibody drug conjugate experience

  • Interpretation of analytical data

  • Teamwork

  • Evidence of Publications and Presentations Skills

Day to Day Responsibilities:

The candidate will work as part of a drug development team with a range of responsibilities including: conjugation reaction development, characterization of reaction profiles and kinetics studies, impurity and residuals removal (e.g. ultrafiltration/diafiltration) and commercial process development activities. This will be a lab-based role, with documentation and presentation of experimental data also expected.

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