Senior Research Associate
4 days ago
Position Summary
INGENIA Therapeutics Inc. is a biotech startup company located in the LlNX building in Watertown, MA, specializing in microvasculature healing. We strive to develop antibody-based therapeutics across multiple disease areas including renal, cardiovascular, and neurodegenerative diseases.
We are seeking a highly motivated
Senior Research Associate
to drive antibody characterization and cell-based functional assays in support of our therapeutic discovery programs. This individual will take a lead role in evaluating antibody leads received from CRO partners, developing in-vitro assays, and optimizing experimental workflows. They will work closely with the Director of Antibody Discovery and Protein Sciences and contribute to both scientific execution and lab coordination in a collaborative startup environment. This position will also support other cell and molecular biology teams as needed and work in a matrixed environment.
Key Responsibilities
· Lead in-vitro characterization of antibody leads from CROs, including binding, potency, and functional activity assessments.
· Develop, optimize, and execute biochemical and cell-based assays (e.g., ELISA, SPR/BLI, FACS, reporter and signaling assays) to support antibody selection and optimization.
· Culture, maintain, and engineer mammalian cell lines for assay development and screening.
· Express, purify, and analyze recombinant antibodies and proteins as needed for internal studies.
· Analyze, interpret, and present experimental data to project teams and leadership.
· Coordinate with CROs to manage study timelines, sample logistics, and data quality.
· Contribute to assay transfer and troubleshooting across internal and external teams.
· Maintain accurate and detailed experimental records in electronic laboratory notebooks.
· Support lab operations, including reagent preparation, equipment oversight, and inventory management.
· Provide training and day-to-day guidance to junior staff or interns.
· Participate in experimental design discussions and help shape assay and workflow strategy.
Qualifications
· Bachelor's or Master's degree in Molecular Biology, Cell Biology, Biochemistry, Immunology, or a related field.
· 4–8 years of relevant biotech or biopharma experience with demonstrated independence in assay development and data interpretation.
· Hands-on experience with antibody or protein characterization (ELISA, FACS, SPR/BLI, or similar).
· Proven ability to troubleshoot and optimize assays and experimental workflows.
· Strong organizational, data analysis, and presentation skills.
· Experience working with or coordinating external research partners (e.g., CROs) preferred.
· Self-motivated, adaptable, and able to thrive in a fast-paced, collaborative startup environment.
INGENIA Therapeutics offers competitive pay, comprehensive benefits and an environment
that encourages the growth and well-being of our employees.
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