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Scientist, Medicinal Chemistry
2 weeks ago
Who We Are:
At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.
What We Do:
Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit
, and follow the company on
,
X
and
. (*in collaboration with AbbVie)
About the Role:
Responsible for the design, synthesis, purification, and characterization of intermediates and bioactive compounds through the use of techniques such as column chromatography (e.g., high performance liquid chromatography, automated normal phase purification), nuclear magnetic resonance and parallel or combinatorial synthesis. Prepares technical reports, summaries, protocols, and quantitative analyses. Responsible for the communication and presentation of results to the project team in order to facilitate effective decision making.
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Your Contributions (include, but are not limited to):
Your Contributions (include, but are not limited to):
- Plays key role in the rapid optimization of lead molecules utilizing modern technology available to medicinal chemists such as automated synthesis and purification
- Participates in a multidisciplinary team committed to the continuous improvement of the lead optimization process as well as the expeditious identification of development compounds
- Designs, plans and conducts synthesis of intermediates and analog libraries as well communicates results to the project or program team
- Other duties as assigned
Requirements:
Requirements:
- BS/BA degree AND 2+ years of relevant experience, including familiarity utilizing any or all of the following: parallel synthesis, lab automation, and purification in the optimization of lead compounds is preferred OR
- MS/MA degree in Synthetic Organic Chemistry preferred AND some similar experience noted above OR
- PhD in Synthetic Organic Chemistry or related field preferred AND some related postdoctoral experience preferred
- Working knowledge of any or all of the following: organic synthesis, parallel synthesis, medicinal chemistry, lab automation, and purification in the optimization of lead compounds is preferred
- Recognizes fundamental anomalies in data points and identifies issues in experiments / processes
- Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals
- Strong knowledge of scientific discipline
- Good knowledge of scientific principles, methods and techniques
- Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools
- Strong computer skills
- Good problem-solving, analytical thinking skills
- Detail oriented
- Ability to meet deadlines
- Excellent communication skills with the ability to collaborate with cross-functional scientists
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
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The annual base salary we reasonably expect to pay is $88,000.00-$127, Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
