Scientist

(ID:

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off (Including Holidays)
• Employee Referral Bonus
• 401K Match
• Tuition reimbursement and professional development opportunities
• Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

Overview

Axle is looking to add a driven, flexible, organized, and meticulous Scientist to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Laboratory of Molecular Microbiology (LMM), Division of Intramural Research (DIR).

Technical Requirements:

• Create, test, and store HIV-1 and HIV-2 virus stocks taking into consideration established biosafety protocols.

• Develop and improve protocols for the processing and differentiation of primary human macrophages and their controlled infection by HIV-1 or HIV-2.

• Perform proteomics studies to identify novel host factors involved in the control of HIV infection.

• Validate newly identified host factors.

• Create stable cell lines expressing host restriction factors and/or knock out endogenous gene expression for the purpose of analyzing their effect on viral replication.

• Conduct research to study the role of nuclear pore proteins for nuclear import of HIV-1 capsids.

• Develop and apply molecular tools for confirming successful gene editing or inactivation.

• Maintain laboratory notebooks with sufficient details for reproducing results and documenting progress to support intellectual property evaluations.

• Maintain laboratory safety.

• Perform mandatory annual refresher training in lab safety and bio safety.

• Maintain accurate sample tracking and data management.

• Perform lab projects independently and assist other lab members with their tasks.

• Discuss and report data in peer reviewed papers and with the Federal Task Leader and scientists.

• Perform problem solving, call technical support to fix problems, initiate service calls or repairs, and interact with field service engineers and field application specialists for repair and optimization of laboratory equipment. 

Specific Qualifications:

• Ph.D. in Biology, Life Sciences or a related discipline. Three (3) years of specialized experience plus a Master's degree is equivalent to a Ph.D.

• Minimum of three (4) years of experience in HIV-1 basic research o Experience working in a BSL2/BSL3 laboratory environment.

• Experience and knowledge of maintaining accurate and detailed records, and knowledge of proper laboratory disposal methods and safety procedures. 

The diversity of Axle's employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact:

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual's assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate's experience, qualifications, skills, and location.

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