Sr Clinical Trial Manager

5 days ago


San Francisco, California, United States Elixir Associates Full time $120,000 - $180,000 per year

Senior Clinical Trial Manager – Oncology – San Francisco

Company:

Our client is a rapidly growing biotechnology company committed to advancing novel Oncology therapies with the potential to address major unmet needs. With a strong pipeline and a dynamic team environment, they are now seeking a Senior Clinical Trial Manager to take a leadership role in overseeing their expanding global clinical portfolio.

The Role:

As a Senior CTM, you will provide strategic oversight and operational leadership across multiple early and late-phase clinical studies. This is a highly visible position where you will not only drive trial execution but also play a key role in refining processes, mentoring junior staff, and ensuring operational excellence as the organization advances through critical phases of development.

As the team continues to grow over the next 18–24 months, this role provides a clear trajectory toward an Associate Director of Clinical Operations position

Key Responsibilities:

  • Lead the planning, execution, and oversight of 2–3 global clinical trials across Phases I–III.
  • Provide guidance and mentorship to junior Clinical Trial Managers and Clinical Operations staff.
  • Partner with senior leadership on portfolio planning and risk mitigation strategies.
  • Manage vendor governance, including CROs and key external suppliers, ensuring accountability for performance.
  • Oversee inspection readiness activities and contribute to regulatory submissions.
  • Act as a trusted point of contact for internal stakeholders, delivering clear, timely trial updates.

Requirements:

  • 5+ years of global Clinical Trial/Project Management experience.
  • Strong track record in Oncology therapeutic areas, preferably within a biotech or mid-size pharma environment.
  • Experience leading teams and providing oversight of global programs across Phases I–III.
  • Demonstrated success in managing trial budgets, timelines, and operational deliverables resulting in regulatory milestones.
  • Must be located in or near the San Francisco area.

What's on Offer:

  • Competitive base salary package, performance bonus, stock options, and comprehensive healthcare.
  • Opportunity to work in a fast-paced, science-driven company making an impact in Oncology.
  • A supportive and collaborative culture that values input at all levels.

If you would like to explore this Senior CTM opening, please connect with me on LinkedIn or contact me directly at dan.-

For more updates on new roles in Clinical Development & Operations, follow the Elixir Associates LinkedIn page.



  • San Francisco, California, United States Trial Library Full time $90,000 - $120,000 per year

    Our mission is to improve health equity by expanding access to cancer precision medicine.About Trial LibraryTrial Library, Inc. is a venture-backed startup founded in 2022 focused on accelerating enrollment and retention to clinical trials with an AI-platform. Trial Library is a mission-driven health technology company dedicated to improving health equity in...


  • South San Francisco, California, United States BioSpace Full time $176,000 - $215,000 per year

    The PositionAt Maze Therapeutics, we believe that precision medicine has the power to transform the lives of patients with both common and rare diseases. As a Senior Clinical Trial Manager (Sr. CTM) at Maze Therapeutics, you'll play a hands-on role in driving the execution of our clinical trials. You'll have the opportunity to lead early- to mid-stage...


  • San Francisco, California, United States Heartflow Full time $110,000 - $150,000 per year

    Heartflow is a medical technology company advancing the diagnosis and management of coronary artery disease, the #1 cause of death worldwide, using cutting-edge technology. The flagship product—an AI-driven, non-invasive cardiac test supported by the ACC/AHA Chest Pain Guidelines called the Heartflow FFRCT Analysis—provides a color-coded, 3D model of a...


  • South San Francisco, California, United States Sutro Biopharma Full time $85,000 - $115,000 per year

    CLINICAL TRIAL ASSOCIATE - CONTRACTSutro Biopharma, Inc. is seeking a driven and talented individual to join our Clinical Operationsteam as we change the future of oncology. While collaborating with cross-functional departments, you will play a key role in maximizing our technology and progressing our novel therapeutics. We are dedicated to making a...


  • South San Francisco, California, United States Sutro Biopharma, Inc. Full time $85,000 - $115,000 per year

    DescriptionCLINICAL TRIAL ASSOCIATE - CONTRACTSutro Biopharma, Inc. is seeking a driven and talented individual to join our Clinical Operations team as we change the future of oncology. While collaborating with cross-functional departments, you will play a key role in maximizing our technology and progressing our novel therapeutics. We are dedicated to...


  • South San Francisco, California, United States SciPro Full time $120,000 - $180,000 per year

    SR MANAGER, CLINICAL CONTRACTS AND OUTSOURCINGHybrid - Menlo Park / Foster City, CA area (2-3days a week)Initial 6mth contract, potential of extensions and/or conversionWe are looking for a Senior Manager to join Clinical Contracts and drive objectives within projects' end-to-end outsourcing to external service providers for current and future clinical...


  • San Francisco, California, United States Trial Library Full time $120,000 - $200,000 per year

    Our mission is to improve health equity by expanding access to cancer precision medicine.About Trial LibraryTrial Library, Inc. is a venture-backed startup founded in 2022 focused on accelerating enrollment and retention to clinical trials with an AI-platform. Trial Library is a mission-driven health technology company dedicated to improving health equity in...


  • San Diego, California, United States Therapeutics, Inc. Full time $110,000 - $145,000 per year

    Who Are We?Founded in 1997 and built upon 27+ years of dermatology-specific experience, we are the only full-service dermatology CRO that takes products from concept to approval. Voted one of San Diego's Top Workplaces, we take pride in maintaining a company culture that values collaboration, diversity of background and thought, and dedicated talent. When...


  • San Diego, California, United States Mirador Therapeutics Full time $85,000 - $105,000 per year

    Mirador is a next-generation precision medicine company focused on immunology and inflammation. The company's Mirador360 TM precision development engine leverages the latest advances in human genetics and cutting-edge data science to rapidly advance new precision medicines for patients living with chronic immune-mediated inflammatory and fibrotic diseases....


  • San Jose, California, United States Pinehurst Surgical Clinic Full time $90,000 - $120,000 per year

    ApplyJob TypeFull-timeDescriptionSUMMARYAs a Clinical Research Coordinator, you will play a pivotal role in contributing to revolutionary treatments for those affected by disorders of the spine. You will aid in the development of this innovative area of medicine by managing and facilitating the day-to-day operations of investigational medical device studies...