Cardiologist Physician Scientist

Job Description Summary

Internal Title: Associate Director or Director

This position will be located in Cambridge, MA and will not have the ability to be located remotely.

#LI-Hybrid

About the role:

The Novartis Institutes for BioMedical Research (NIBR) is the innovation engine of Novartis that collaborates across the company and beyond, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Translational Medicine (TM) is the clinical research arm of NIBR, and includes about 900 associates globally. TM plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, and bridging drug discovery and clinical application.

The TM Discovery & Profiling (TMDP) is a group of physicians and clinical researchers who drive innovative science from discovery to the patient through the selection, profiling, and effective development of medicines. Translational medicine experts oversee Phase 1 and 2 clinical trials to demonstrate proof-of-concept (PoC) in patients, as well as support for Phase 3 development. Translational medicine experts are key and highly visible members of global cross-functional project teams that design and implement early research and
discovery projects, that then culminate in clinical PoC studies. Translational medicine experts collaborate with colleagues in biology and chemistry to identify targets in diseases with significant unmet medical needs and provide input on likely clinical development pathways. The PoC studies led by our translational medicine experts are among the most critical steps in drug development at Novartis. After PoC and if the program proceeds to full development, the translational medicine expert continues as a key member of the full development team up to and including registration.

As a Cardiovascular Metabolism (CVM) TM Expert, you will collaborate with the CVM TM Head or other experienced TM Expert to develop high value decision-strategies for the Translational Medicine component of drug development projects and lead global cross-functional project teams through the PoC phase and beyond.

Job Description

Key Responsibilities:

• Lead global project teams through PoC phase to drive implementation of the PoC strategy; participate in project teams through program life cycle from NTRC to registration

• Responsible for clinical portions of the Integrated Development Plan (IDP) through PoC.

• Acts as medical monitor for one or more clinical studies

• Communicate clinical team matters to project teams and relevant decision boards (Disease Area Decision Board).

• Convene relevant (internal and external) leaders to consider proposed approach to PoC.

• Evaluate clinical centers and foster communication with crucial collaborating investigators

• Oversee publication and external presentation of PoC clinical study results

• Accountable for compound related biomarker strategies; work closely with biomarker experts in implementation

• In collaboration with research scientists identify, develop and implement strategy for preclinical support of program related objectives; this includes assessment of medical need, proposal of clinical development pathways, and review of preclinical data for clinical implications and other relevant activities

• Participate in team presentations to Health Authorities as TM Expert

Essential Requirements:

• Doctoral degree, MD required with clinical subspecialty training preferred in cardiovascular disease or endocrinology/metabolic disease; Additional PhD/post-doctoral equivalent research preferred.

• At least 1-2 years' experience in a pharmaceutical/biotech company, CRO, or academic medical center, or related experience; 5 plus years to be considered for Director level.

• Recognized for medical expertise.

• Recognized for scientific expertise: respected by colleagues internally and externally, have made significant contributions to the field and created / established new concepts; record of high quality publications in international scientific journals.

• Excellent written and oral communication/presentation skills.

• Independence: Able to work independently on study planning and execution, and with supervision on project planning.

• Leadership of Collaborations: Able to lead multidisciplinary teams in a matrix organization.

• Innovation: Seeks out new clinical discovery opportunities and PoC approaches.

• Additional consideration for candidates with advanced research experience in data science, genetics/genomics, AI or digital methods in electrocardiography and/or cardiovascular imaging.

• Demonstrated passion for science.

This is a dual level posting. The final level and title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between: $204,400 to $379,600/year at the Associate Director level and between $236,600 to $439,400/year at the Director level; however, while salary ranges are effective from 1/1/25 through 12/31/25, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

$204,400.00 - $379,600.00

Skills Desired

Clinical Trials, Data Analysis, Data Monitoring, Drug Development, Drug Discovery, Medical Strategy, People Management

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