Senior Oncology Account Manager

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

Immunome is seeking a Senior Oncology Account Manager to drive territory-level sales performance in preparation for and following the potential launch of varegacestat in desmoid tumors. This role will be responsible for building strong relationships with healthcare providers, executing brand strategy at the local level, and ensuring that patients and physicians in the territory have the information and support needed to consider varegacestat as a treatment option. This work is grounded in authentic patient centricity, keeping the needs of people living with desmoid tumors at the center of every decision.

As a core member of the U.S. Commercial organization, this individual will partner cross-functionally with Market Development, Marketing, Market Access, and Medical Affairs to deliver a compliant, insight-driven customer experience. The mission of this role is to achieve territory sales objectives while establishing Immunome as a trusted commercial and scientific partner within the desmoid tumor community. Success in this role depends on the ability to extend trust — to physicians, teammates, and cross-functional partners alike — as the foundation of every relationship.

Responsibilities

Territory Sales Execution

• Achieve or exceed territory sales goals for varegacestat in alignment with the national brand strategy.
• Develop and execute a territory business plan that identifies priority accounts, targets, and call plans.
• Deliver clear, compliant, and compelling clinical and value-based selling messages to healthcare providers.
• Maintain a deep understanding of the desmoid tumor treatment landscape, referral patterns, and local standards of care. This requires the ability to scan, adjust, and focus as market dynamics, referral patterns, and provider needs evolve.
• Track and report territory activity, call metrics, and business results using approved CRM tools.

Customer Engagement & Relationship Building

• Build and maintain strong, compliant relationships with physicians, nurses, and other office staff within the territory.
• Identify and engage local key opinion leaders, sarcoma specialists, and multidisciplinary care teams.
• Support compliant company-approved promotional speaker programs, in-office educational activities, and other healthcare provider engagements in accordance with applicable regulations and company policies. Serve as a responsive, trusted resource for customer questions, connecting providers to Medical Affairs or Market Access as appropriate.

Cross-Functional Collaboration

• Partner closely with:
  • Market Development on KOL engagement and market insight sharing
  • Marketing on execution of brand strategy and promotional materials
  • Market Access on payer coverage, reimbursement support, and patient access
  • Medical Affairs to ensure compliant scientific exchange
• Share territory-level insights and competitive intelligence with sales leadership and internal stakeholders.

Compliance & Professionalism

• Conduct all territory activities in strict accordance with applicable laws, company policies, industry regulations, and legal/regulatory guidelines (including FDA promotional rules, the PhRMA Code and OIG guidance).
• Maintain accurate expense reporting, sample accountability (if applicable), and territory documentation.

Qualifications &l