Systems Biology Staff Scientist

7 days ago


Frederick, United States Alakaina Foundation Family of Companies Full time

DESCRIPTION OF RESPONSIBILITIES:Generate and execute protocols for the Systems Biology Branch at the Center for Genome Sciences. Perform and develop protocols for transcriptomic and proteomic (bulk, single cell and spatial), metabolomic in samples from in vitro cultures, animal model or human samples for host respond characterization to pathogen infection or treated with a specific Medical Countermeasure.Perform protocols for epigenetic modification in nucleic acids (RNA and DNA). Preparation of transition packages/technical reports/training documentation.Perform protocols using micro physiological systems (MPS), including ex-vivo tissues, organs on a chip, spheroids, organoids, and tissue 3D printing. Perform in vitro cell culture techniques to support the tasks.Assist in the preparation of transition packages, technical reports, and training documentation. Perform technical literature searches to support and update these protocols and techniques.Prepare technical reports and manuscripts for publication. Provide Quarterly and Annual Reports for all associative projectsEstablish a biosample repository for evaluation and verification. Maintain a biosample repository for testing both surveillance verification as well as the new surveillance platforms.Provide a Project Report outlining protocols, data and standard operating procedures for responsible projects as requested.Ensure reagents in the lab are not expired and ordered periodically to avoid shortage in reagents and stops in processes. Maintain reagent, sample, and intermediary processes products inventory updated and stored in the designated areas, following biosafety guidance’s and CGS protocols. Receive and appropriately storage reagents and samples delivered to the CGS. Support generation of all associative documentation for supply and equipment acquisition as necessary to complete objectives.The number of deliverables required will vary per year depending on the number of funded projects available, but the typical workload is management and execution of 2-4 projects per year.Participate in all activities pertinent to lab performance and safety, including weekly lab clean-up to avoid contaminations, be primary, secondary or tertiary point of contact for equipment and/or laboratory spaces (POC will be contacted by phone during emergencies, such as alarms or loss of power, and need to respond according to emergency plan for the CGS). Contact commercial companies and/or USAMRIID Medical Maintenance or Clinical Engineering (CEB) when an instrument is malfunctioning or needs periodical PM, and escort engineers during the scheduled visit at USAMRIID.Other duties as assigned.REQUIRED DEGREE/EDUCATION/CERTIFICATION:PhD in biological or life sciencesREQUIRED SKILLS AND EXPERIENCE:Minimum of 3 years of experience in the field or in a related area.Direct experience with Western blot/ELISA, molecular and system biology techniques, nucleic acid and protein extractions with quality check, PCR, microbiome, metabolomics, pyrosequencing, statistics and data analysis and visualizations.Must have knowledge of commonly used concepts, practices, and procedures within this particular field.Must be proficient with statistical analyses.REQUIRED CITIZENSHIP AND CLEARANCE:U.S. CitizenMust pass NACI background check.Must be willing to work in a BSL 3/4 laboratory.Must be eligible to enroll in the BPRP and CS-PRP programs. ​The Alaka`ina Foundation Family of Companies (FOCs) is a fast-growing government service provider. Employees enjoy competitive salaries. Eligible full-time employees enjoy a 401K plan with company match; medical, dental, disability, and life insurance coverage; tuition reimbursement; paid time off; and 11 paid holidays.



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