Staff Scientist

3 days ago


Aiken, United States Baylor College of Medicine Full time

SummaryThe Sedlazeck Lab is seeking a highly motivated Staff Scientist with strong computational and algorithmic expertise to lead and support cutting-edge research in long-read genomics, tandem repeat (TR) analysis, and population-scale variant discovery. Our group develops novel methods and performs large-scale analyses across diverse cohorts, leveraging PacBio HiFi, Oxford Nanopore, and graph-based genome technologies.Job DutiesDevelop, implement, and optimize algorithms and computational methods for structural variant (SV), tandem repeat (TR), and methylation analysis in long-read sequencing data.Lead population-scale analyses involving thousands of long-read genomes, including data QC, variant calling, benchmarking, and integration across platforms.Design and execute computational workflows for SV and TR discovery, merging, harmonization, and interpretation across large cohorts.Work independently to drive multiple concurrent projects, including collaborations with national and international consortia (e.g., All of Us, TOPMed, GREGoR). Contribute to manuscript writing, grant applications, and presentation of results at internal and external meetings.Mentor trainees and support a collaborative, high-impact research environment. Perform other job related duties as assigned.Minimum QualificationsDoctoral Degree. Experience may not be substituted in lieu of degree.Three years of post doctoral research experience.  Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.   SN



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