Current jobs related to Senior Medical Director, Kidney Disease, Early Clinical Development CVRM - Gaithersburg - AstraZeneca
-
Gaithersburg, MD, United States AstraZeneca Full timeThe Senior Medical Director will be focused on Kidney Disease and related conditions that impact kidney functionIn this role, you will have the opportunity to work at the forefront of early clinical and translational research within CVRM. In a multidisciplinary environment, you will play a key role in progressing a rich and diverse pipeline of both small and...
-
Gaithersburg, MD, United States AstraZeneca Full timeThe Senior Medical Director will be focused on Kidney Disease and related conditions that impact kidney functionIn this role, you will have the opportunity to work at the forefront of early clinical and translational research within CVRM. In a multidisciplinary environment, you will play a key role in progressing a rich and diverse pipeline of both small and...
-
Gaithersburg, MD, United States AstraZeneca Full timeThe Senior Medical Director will be focused on Kidney Disease and related conditions that impact kidney functionIn this role, you will have the opportunity to work at the forefront of early clinical and translational research within CVRM. In a multidisciplinary environment, you will play a key role in progressing a rich and diverse pipeline of both small and...
-
Gaithersburg, MD, United States AstraZeneca Full timeThe Senior Medical Director will be focused on Kidney Disease and related conditions that impact kidney functionIn this role, you will have the opportunity to work at the forefront of early clinical and translational research within CVRM. In a multidisciplinary environment, you will play a key role in progressing a rich and diverse pipeline of both small and...
-
Gaithersburg, United States AstraZeneca Full timeIn Cardiovascular, Renal & Metabolism, we are investigating the drivers of CVRM disease progression through ground breaking scientific methods and data-driven drug discovery and development approaches. In this context, the Translational Science and Clinical Development team are investigating a wide range of different drug modalities from a rich CVRM...
-
Gaithersburg, United States AstraZeneca Full timeWe are seeking a passionate and accomplished Principal Scientist with expertise in skeletal muscle physiology, metabolism and drug discovery to join our vibrant research community Metabolism Bioscience Team within Research and Early Development CVRM.CVRM is one of the three main therapeutic research areas within BioPharmaceuticals AstraZeneca which deliver...
-
Gaithersburg, United States AstraZeneca Full timeAssociate Director, Early Commercial StrategyAt AstraZeneca, we turn ideas into life-changing medicines. Working here means being entrepreneurial, thinking big, and working together across disciplines to make the impossible a reality. The Biopharmaceuticals Business Unit (BBU) bridges science and commercialintegrating therapy area and product strategies from...
-
Gaithersburg, United States AstraZeneca Full timeExecutive Director, Clinical Operations (Early Oncology)The Executive Director, Clinical Operations, is a transformative leader charged with setting the strategic direction, operational excellence, and future vision for Early Oncology (EO) clinical programs within the Clinical Programs & Study Operations (CPSO) organization. This role is at the helm of...
-
Executive Director, Clinical Operations
1 week ago
Gaithersburg, United States AstraZeneca Full timeExecutive Director, Clinical Operations (Early Oncology)The Executive Director, Clinical Operations, is a transformative leader charged with setting the strategic direction, operational excellence, and future vision for Early Oncology (EO) clinical programs within the Clinical Programs & Study Operations (CPSO) organization. This role is at the helm of...
-
Head of Early Assets, Hematology
3 weeks ago
Gaithersburg, United States AstraZeneca Full timeHead Of Early Assets, HematologyAt AstraZeneca, our ambition is to transform outcomes for patients with hematologic malignancies and related hematology conditions. We aim to reset standards of care by advancing innovative therapies across a broad pipeline inclusive of assets, including bispecific T-cell engagers (TCEs), antibody-drug conjugates (ADCs), and...
Senior Medical Director, Kidney Disease, Early Clinical Development CVRM
2 weeks ago
The Senior Medical Director will be focused on Kidney Disease and related conditions that impact kidney function. In this role, you will have the opportunity to work at the forefront of early clinical and translational research within CVRM. In a multidisciplinary environment, you will play a key role in progressing a rich and diverse pipeline of both small and large molecules in numerous active clinical programs. Who We AreIn the Cardiovascular, Renal & Metabolism (CVRM)Translational Medicine & Clinical Development (TSCD) department, we are investigating the underlying factors contributing to CVRM disease progressionusing advanced scientific methodologies and data-driven drug discovery. In this context, we are evaluating a wide range of different drug modalities from our rich CVRM portfolio of compoundsacross kidney diseasepatient populations.TSCD is where science meets clinical drug development with a focus upon delivering innovative, early phase clinical studies and accelerating human target validation while collaborating closely with our late phase clinical development and regulatory colleagues who guide our pivotal phase 3 clinical studies.What You Will DoYou will be responsible for managing and leading to early phase I-II global clinical trials and related clinical research projects for compounds that are targeting kidney disease, as well as serving as an expert on the design, conduct, monitoring, data interpretation, and reporting of these studies.Additionally, you will work on cross-functional teams within our TSCD group and across the broader globalCVRM organization that are framing our strategies and development plans for compounds that are targeting cardiovascular diseases such asHeart Failure,as well as major metabolic disorders, such as Type 2 Diabetes, Obesity, and Metabolic Dysfunction-Associated Steatohepatitis, given that these disorders intersect with chronic kidney disease and influence disease progression.Responsibilities include: Lead early Phase I–II global trials in kidneydisease: clinical strategy, protocol design, studyconduct, monitoring, data interpretation, and reporting, ensuringscientificintegrity, patient safety, and regulatorycompliance.Provide clinical leadership to cross-functional teams; integratepreclinicalinsights (targetselection, pharmacology, in vivo/in vitro data) into early clinical plans and seamless transitions to late phasedevelopment.Contribute to regulatoryinteractions and documentation (, CTAs, INDs, safetyupdates, annualreports).Advance the development and validation of nonclinical and surrogateendpoints (includingimaging and biomarkers).Represent TSCD internally and externallythrough presentations, publications, and scientific forums; engagewithexternal experts and translate insightsintostrategy and study design.Helpevolvetrial operations and site engagement to improve speed, quality, and inclusivity in early studies.Collaborateacross CVRM on programs in heartfailure, type 2 diabetes, obesity, and metabolicdysfunction-associatedsteatohepatitis, given theirintersectionwithkidneydisease.Basic Qualifications: MD, MBBS or MD/PhD withestablishedclinical or research expertise in in the treatment of kidney diseases.Minimum of 5yearsof clinical research in academia and/or the pharmaceutical/biotechnologyindustry.Experience designing, executing, monitoring, interpreting, and overseeingsafety in early clinical and translationaltrials preferred.Strong command of biomarkers, surrogateendpoints, and biostatistics, supported by a robust publication record.Welldeveloped interpersonal skills, effective teamwork, and the ability to engagestakeholderseffectivelyacrossfunctions, geographies, and disciplines.Why AstraZeneca?Here, we need leadership at every level – Physicians who not only have clinical and scientific expertise, but also the ability to build a case, engage multiple partners, and communicate effectively with different audiences. With that kind of remit comes great responsibility. We truly believe that everyone contributes with an outstanding set of competence. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximize your skills, abilities and contribution.The annual base pay for this position ranges from $280,895 – $421,342 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and bold world. Date Posted05-Sep-2025Closing DateOur mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
