Postdoctoral Fellow-MSH-32076-162

DescriptionSalary: Starting salary per UAW agreement $74,692Department: 866 – Department of Immunology and Immunotherapy Location: Icahn – 1425 Madison Avenue, 11th Floor, New York, NY 10029 ResponsibilitiesThe Sun Laboratory is seeking highly motivated postdocs to lead projects aimed at developing innovative gene/drug delivery systems for applications in immunotherapy and in vivo gene writing. The research will involve exploring novel non-viral delivery technologies to achieve site-specific insertion of therapeutic genes in vivo, with the goal of advancing next-generation gene editing and immunotherapy treatments for severe diseases such as cancer, infectious diseases, and genetic disorders. This project will contribute to understanding the challenges and potential solutions associated with precise gene delivery and therapeutic modulation of the immune system.Goals/Outcomes of the Research Project: Advancing next generation gene editing and immunotherapy treatments for severe diseases such as cancer, infectious diseases, and genetic disorders. This project will contribute to understanding the challenges and potential solutions associated with precise gene delivery and therapeutic modulation and the immune system.QualificationsTechnical Duties: (include any protocols) Develop, optimize, and analyze novel LNP formulations.Design and synthesize new biomaterials for drug/gene delivery.Design and conduct in vivo experiments to evaluate the delivery efficiency and therapeutic impact of the new delivery system.Perform CRISPR gene editing protocols.Conduct immunological assays, including flow cyttmetry, ELISA, ELISPOT, and cytokine profiling, to assess immune responses.Perform molecular biology techniques, such as PCR, qRT-PCR, Western blotting, and sequencing, to analyze gene expression and editing outcomes.Collaborate with team members to design and implement experiments, analyze data, and troubleshoot technical challenges.Maintain accurate and detailed records of experiments, protocols, and results in accordance with lab standards.Supervise and mentor junior lab members, including graduate students and technicians, as required.Critically analyze data quality and results, and communicate findings to scientists and non-specialists.Write or assist in writing scientific papers and grants.Qualifications:Ph.D. Degree requiredExperience working in a research laboratory settingThis position is covered by a collective bargaining agreement between the ISMMS and the Sinai Postdoctoral Organizing Committee - UAW. Employer DescriptionStrength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. About the Mount Sinai Health System: Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally. Equal Opportunity Employer The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.CompensationThe Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $72500 - $80000 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.