Senior Scientist, In-vitro Pharmacology/Electrophysiology
7 days ago
Job DescriptionGeneral Summary:Vertex Pharmaceuticals has an exciting opportunity for a Senior Scientist to join the In-vitro Pharmacology/Electrophysiology group within the Pharmacology Department. We are seeking a motivated, creative, and innovative scientist with a deep understanding of ion channel physiology and pharmacology. A successful candidate will have broad, hands-on experience using a range of in vitro cellular assays. Preference will be given to candidates with extensive experience with patch clamp electrophysiology, MEA, Ca2+-imaging etc. working with primary cells, including human cells. Experience with data analytics and computational modeling & simulation is highly valued. A successful candidate will demonstrate a strong desire to collaborate within a multidisciplinary drug discovery team.Key Duties and Responsibilities:Develop, validate and execute in-vitro assays, including electrophysiology assays, to support drug discovery projects.Analyze and interpret complex and multidimensional data and effectively document and communicate results.Provide novel insight through data analytics and computational modeling & simulation.Work effectively in a multi-disciplinary team environment and have excellent organizational and communication skills.Knowledge and Skills:Extensive knowledge of ion channel physiology and pharmacology and applications to drug discovery.Experience with single channel recording and multiple patch clamp configurations (inside-out, cell-attached, etc).Demonstrated experience with MEA.Ability to analyze complex datasets using MATLAB, Python, etc.Background in Neuroscience or Pain and familiarity with drug discovery.Ability to navigate and thrive in a fast-paced, highly matrixed work environment.Strong desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society.Demonstrates ability to solve complex problems to attain crucial Project goalsHighly effective verbal and written communication skills and attention to detail in preparing business critical documents (e.g. experimental records, SOPs, and study reports).Education and Experience:Degree in Physiology, Pharmacology, or related fieldPhD and 3+ years, or Master's and 5+ years, or Bachelor's and 8+ years.In depth experience in the design, execution, and interpretation of manual and/or automated patch-clamp electrophysiology studies.Experience with computational modeling & simulation of ion channel behavior and drug combination pharmacology.
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San Diego, United States Neurocrine Biosciences Full timeTEMP - Associate Scientist, In Vitro Pharmacology page is loaded## TEMP - Associate Scientist, In Vitro Pharmacologyremote type: On-Sitelocations: US CA San Diegotime type: Full timeposted on: Posted Todayjob requisition id: R6222## Who We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our...
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San Diego, United States Neurocrine Biosciences Full timeTEMP - Associate Scientist, In Vitro Pharmacology page is loaded## TEMP - Associate Scientist, In Vitro Pharmacologyremote type: On-Sitelocations: US CA San Diegotime type: Full timeposted on: Posted Todayjob requisition id: R6222## Who We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on...
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San Diego, United States Neurocrine Biosciences Full timeA leading biopharmaceutical company is seeking a highly motivated Associate Scientist to join their In Vitro Pharmacology team in San Diego. The role focuses on optimizing and executing in vitro pharmacology assays and requires a BS/BA with over 3 years of relevant experience or a MS/MA in Molecular Pharmacology. Ideal candidates have hands-on experience...
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San Diego, United States Neurocrine Biosciences Full timeA leading biopharmaceutical company is seeking a highly motivated Associate Scientist to join their In Vitro Pharmacology team in San Diego. The role focuses on optimizing and executing in vitro pharmacology assays and requires a BS/BA with over 3 years of relevant experience or a MS/MA in Molecular Pharmacology. Ideal candidates have hands-on experience...
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San Diego, United States Neurocrine Biosciences Full timeA biopharmaceutical firm is seeking a highly motivated Associate Scientist in San Diego, California. The role involves optimizing and executing in vitro pharmacology assays. Candidates should have a BS/BA degree and over 3 years of relevant experience, or a Master's degree with comparable experience. Responsibilities include data analysis, functional assays,...
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In Vitro Pharmacology Scientist – Lead Discovery
2 weeks ago
San Diego, United States Neurocrine Biosciences Full timeA biopharmaceutical firm is seeking a highly motivated Associate Scientist in San Diego, California. The role involves optimizing and executing in vitro pharmacology assays. Candidates should have a BS/BA degree and over 3 years of relevant experience, or a Master's degree with comparable experience. Responsibilities include data analysis, functional assays,...
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In Vitro Pharmacology Scientist: Lead Optimization
19 hours ago
San Diego, United States Neurocrine Biosciences Full timeA leading biopharmaceutical company in San Diego is seeking a highly motivated Associate Scientist. The role involves optimizing and executing in vitro pharmacology assays, critical data analysis, and maintaining documentation. Candidates should have a BS/BA degree with over 3 years of experience in relevant biological assays, alongside strong communication...
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Scientist, In Vitro Pharmacology
7 days ago
San Francisco, California, United States Work In Biotech Full timeJob Title: Research ScientistCompany:Stealth-mode Biotech (Protein-based Radioligand Therapeutics)About the CompanyWe are an early-stage, venture-backed biotechnology company operating in stealth mode, developing a novel platform for protein-based radioligand therapies. Our mission is to transform the precision oncology landscape by integrating protein...
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Director, Electrophysiology
2 weeks ago
San Diego, United States Vertex Full timeJob DescriptionGeneral Summary:Vertex Pharmaceuticals has an exciting opportunity for a Director to lead the Electrophysiology group within the Pharmacology Department. This is an onsite position at our San Diego drug discovery site.The Director will have an impressive track record of accomplishments in drug discovery and project advancement and will be...
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San Diego, United States Neurocrine Biosciences Full timeWho We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. What We Do:Neurocrine Biosciences is a leading...
