Computational Protein Engineer
6 days ago
This position is responsible for developing, planning, and developing an in-silico platform for antibody and other protein engineering in collaboration with other scientists in the group and across the company. The incumbent will be responsible for developing workflows for the de novo design of antibodies and proteins. This position assists in identifying and implementing departmental initiatives and strategies. This position may/will supervise the work of others directly and/or across interdisciplinary teams.
DUTIES AND RESPONSIBILITIES:- Develop an in-silico platform for antibody and other protein engineering in collaboration with other scientists in the group and across the company.
- Develop computational pipelines for protein structure determination using structural and/or sequence-based methods and/or artificial intelligence methods (e.g. Rosetta, AlphaFold).
- Develop computational pipelines for protein docking and antibody epitope mapping.
- Demonstrate ability to combine data from different sources and analyze these or incorporate these into multidimensional optimization of protein:protein interactions.
- Lead a technical team to implement computational pipelines in protein design, engineering, or prediction.
- Critically evaluate experimental data and incorporate this knowledge into design.
- Provide input to the management team to identify, develop, and execute departmental initiatives and strategies.
- Lead technical team(s) to accomplish project goals and manage/coordinate work of other team members.
- Present findings/analyses and any associated issues/solutions to peer groups and managers; make recommendations for project advancement.
- Lead cross-functional initiatives with other business units on projects/products or associated deliverables.
- Specific duties may vary depending upon departmental requirements.
- Master's degree (PhD preferred) in structural bioinformatics, molecular biology, bioengineering, biophysics, computational biology, or related field with industry experience.
- Expertise with protein and antibody modeling, including antigen-antibody interactions.
- Publications in the form of high-profile papers/patents within protein prediction or de novo protein design, including antibody or enzyme engineering.
- Experience with artificial intelligence and/or machine learning methods is desirable.
- Proven record of remaining current, learning new techniques/research in areas of computational biochemistry.
- Superior scientific fundamentals and analytical background.
- Ability to work independently and in teams, and to collaborate with external parties.
- Excellent communication skills and the ability to work in a highly dynamic and collaborative environment.
- Expert problem-solving skills and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion.
- Strong analytical skills with the demonstrated ability to gather and evaluate complex data and information and develop a recommendation and plan of action.
- Excellent organizational, planning, and time management skills required, with the ability to manage multiple and often changing priorities and issues of varying complexity while meeting time-sensitive deadlines and deliverables.
- Demonstrated propensity to be creative, collaborative, proactive, and self-motivated in the execution and completion of assigned tasks.
- Exceptional communication (written and verbal) skills regardless of the format (e.g., documents, public speaking situations, presentations, etc.).
- Attention to detail with demonstrated commitment to excellence and performance.
- Proven proficiency with Microsoft Office (i.e., Word, Excel, PowerPoint, Outlook).
- While performing the duties of this job, the individual is frequently required to sit and stand for long periods. The individual is occasionally required to walk; use hands and fingers to operate, handle, or feel objects, tools, or controls; reach with hands and arms.
- Up to 10% of the day may be spent at a laboratory bench.
- There are aspects of the position’s duties that require a person in this role to work at heights above four (4) feet on occasion and move/lift up to 25 pounds.
- Laboratory environment working with chemical reagents and performing some Biosafety Level 2 work.
- May involve handling of BSL-2 materials and organisms including human blood and/or blood products.
-
Gaithersburg, United States AstraZeneca Full timeHead of Antibody Drug Conjugates, Biologics Engineering Locations: Gaithersburg, MD/Waltham, MA Are you a visionary in drug development with a passion for pioneering new biologics? Biologics Engineering is seeking a highly accomplished and innovative drug developer to join our team as a Head of Antibody Drug Conjugates. In this pivotal role, you will be...
-
Computer Scientist
1 month ago
Gaithersburg, United States National Institute of Standards and Technology Full timeSummary The Department of Commerce ranked top 5 in the 2023 Best Places to Work in the Federal Government amongst large agencies for the 12th year in a row! The ranking showcases the Department's continued commitment to increasing our employee engagement, employee satisfaction, and positive perceptions towards diversity, equity, accessibility, and inclusion....
-
Computer Scientist
2 weeks ago
Gaithersburg, United States National Institute of Standards and Technology Full timeSummary The Department of Commerce ranked top 5 in the 2023 Best Places to Work in the Federal Government amongst large agencies for the 12th year in a row! The ranking showcases the Department's continued commitment to increasing our employee engagement, employee satisfaction, and positive perceptions towards diversity, equity, accessibility, and inclusion....
-
Senior Biotechnology Professional
2 weeks ago
Gaithersburg, Maryland, United States Fladger Assoc. Inc. Full timeJob Description: Senior ScientistWe are looking for an experienced Senior Scientist to join our team at Fladger Assoc. Inc. in Gaithersburg, MD.Job Summary:The successful candidate will be responsible for leading the development of late-stage formulations for biologic products, including design and execution of formulation risk assessments and...
-
Bio-Manufacturing Associate
3 weeks ago
Gaithersburg, Maryland, United States Meet Full timeJob OverviewWe are seeking a highly motivated Bio-Manufacturing Associate to join our team in Gaithersburg, MD. The estimated annual salary for this position is $80,000 - $100,000.The successful candidate will work on reproducing chromatography and filtration processes to support process development/characterization. They will also maintain and monitor...
-
Electrical Engineering Co-Op
7 days ago
Gaithersburg, United States Patton Electronics Full timeDescription: Patton is seeking a talented and motivated Electrical or Computer Engineering student to join our dynamic team as an Electrical Engineering Co-Op. In this role, you will contribute to the design and development of our cutting-edge data communications and networking products. You will have the opportunity to work closely with experienced...
-
Geotech Engineer
7 days ago
Gaithersburg, United States Merit 321 Full timeTitle: Geotech Engineer Location: Gaithersburg, MD Clearance: N/A Summary Our client is currently seeking applicants interested in an entry level Geotechnical Engineer at our Gaithersburg office. The engineer will be part of the team under the direct responsible charge of a Licensed Engineer. Work may be part of a team or solo. Work opportunities will...
-
Data Science and Engineering Lead
3 weeks ago
Gaithersburg, Maryland, United States Nexcepta, Inc Full timeLead Data Science and Engineering RoleNexcepta, Inc. seeks a skilled Research Scientist to lead our data science and engineering efforts in developing innovative technologies. As a key member of our interdisciplinary team, you will participate in research activities, write technical documents, develop software and prototypes, and collaborate with experts to...
-
Research Engineer
4 weeks ago
Gaithersburg, Maryland, United States National Institute of Standards and Technology Full time**Research Opportunities**The National Institute of Standards and Technology (NIST) is a premier research organization that drives innovation and industrial competitiveness by advancing measurement science, standards, and technology. We are seeking a talented Research Engineer to join our team.Job DescriptionWe are looking for a skilled Research Engineer to...
-
Mechanical Engineer
3 days ago
Gaithersburg, United States Ted Ross Consulting LLC Full timeJob DescriptionJob DescriptionTRC Engineering is an area leader with a team of experienced facility engineering professionals, specializing in Mechanical, Electrical and Plumbing systems analysis, trouble shooting, maintenance planning, design and retrofitting as well as other engineering practices. We are currently looking for Mechanical Engineers to join...
-
Mechanical Engineer
7 days ago
Gaithersburg, United States Ted Ross Consulting LLC Full timeJob DescriptionJob DescriptionTRC Engineering is an area leader with a team of experienced facility engineering professionals, specializing in Mechanical, Electrical and Plumbing systems analysis, trouble shooting, maintenance planning, design and retrofitting as well as other engineering practices. We are currently looking for Mechanical Engineers to join...
-
Embedded Software Engineer
6 months ago
Gaithersburg, United States She Recruits, LLC Full timePosition: Embedded Software EngineerLocation: Gaithersburg, MD Salary: 150k-170k About the Role: As an Embedded Software Engineer, you will be instrumental in designing, developing, and optimizing embedded software solutions for our cutting-edge autonomous driving systems. Your work will directly impact the advancement of technology in the aerospace sector....
-
Mechanical Engineer
7 days ago
Gaithersburg, United States ZipRecruiter Full timeJob DescriptionJob Description TRC Engineering is an area leader with a team of experienced facility engineering professionals, specializing in Mechanical, Electrical and Plumbing systems analysis, trouble shooting, maintenance planning, design and retrofitting as well as other engineering practices. We are currently looking for Mechanical Engineers to join...
-
IT Network Engineer
2 weeks ago
Gaithersburg, Maryland, United States Adventist HealthCare Full timeJob Summary: Adventist HealthCare is seeking a highly skilled IT Network Engineer to join our team. As a Network Engineer, you will be responsible for designing, implementing, and maintaining the organization's network infrastructure. This includes configuring and troubleshooting network devices, ensuring the security and integrity of the network, and...
-
Software Engineering Manager
3 weeks ago
Gaithersburg, Maryland, United States Blue Cross Blue Shield companies Full timeWelcome to Synergie Medication Collective, where we are revolutionizing the way we approach medication contracting. As a leading-edge organization founded by Blue Cross and Blue Shield affiliated companies, we are committed to improving affordability and access to costly medical benefit drugs for millions of Americans. We are seeking a seasoned Principal...
-
Formulation Development Lead
2 weeks ago
Gaithersburg, Maryland, United States Fladger Assoc. Inc. Full timeJob Title: Senior ScientistWe are seeking a highly skilled Senior Scientist to join our team at Fladger Assoc. Inc. in Gaithersburg, MD.Job Summary:The selected candidate will be responsible for leading the development of late-stage formulations for biologic products. This includes designing and executing formulation risk assessments, characterization...
-
Engineering Services Coordinator
3 days ago
Gaithersburg, Maryland, United States Lincoln Property Company Full timeJob SummaryWe are seeking a highly skilled Building Engineer to join our team at Lincoln Property Company. The successful candidate will be responsible for the operations and maintenance of our buildings, ensuring maximum energy efficiency, cost effectiveness, and engineering services to our tenants. This is a full-time position with a competitive salary...
-
Automation Systems Engineer
3 weeks ago
Gaithersburg, Maryland, United States Meso Scale Discovery Full timeJob SummaryThe position of Automation Systems Engineer at Meso Scale Diagnostics is a challenging and rewarding opportunity for experienced professionals in the field of automation engineering. The ideal candidate will have a strong background in designing, developing, and testing automated assembly equipment, as well as experience in project planning,...
-
Technical Engineering Manager
3 weeks ago
Gaithersburg, Maryland, United States Meso Scale Discovery Full timeAutomation Systems Engineer Job RequirementsTo be successful in this role, you should possess a strong background in automation engineering, with experience in designing, developing, and testing automated assembly equipment. You should also have excellent problem-solving skills, with the ability to analyze and troubleshoot complex automation systems.Key...
-
Database Engineering Professional
2 weeks ago
Gaithersburg, Maryland, United States Resource Informatics Group Inc Full timeAbout the Role:We are looking for an experienced Database Engineering Professional to join our team at Resource Informatics Group Inc. As a key member of our engineering group, you will be responsible for designing and implementing scalable and secure database solutions on Azure.Main Responsibilities:- Develop and administer MS SQL databases in an Azure...