Senior Data Scientist

5 days ago

South San Francisco, United States R&D Partners Full time
Job DescriptionJob Description

R&D Partners is seeking to hire a Senior Data Scientist in South San Francisco, CA

Your main responsibilities as a Senior Data Scientist:

Our client is developing the first high-performance, predictive blood-based test for Alzheimer’s Disease (AD) and related dementias that directly assays mRNA transcripts from the brain via its platform technology of cell-free messenger RNA (cf-mRNA) analysis and machine learning. This next-generation novel liquid biopsy technology enables non-invasive measurement of the dynamic biology of organs throughout the body, including the brain. Our precise understanding of the underlying pathways of disease will transform AD disease care and treatment.

*This is not a remote position - this role is fully on site.

 

Key Responsibilities:

Lead innovation in secondary and tertiary analysis of cf-RNA sequencing data, focusing on delivering rigorous and reproducible results

  • Develop and implement advanced methods for differential gene expression analysis, pathway analysis, and enrichment analysis, optimizing for accuracy and biological insights
  • Build, train, test, and validate predictive models, including logistic regression, random forests, and neural networks, as well as leverage existing RNA-seq large language models (LLMs) for inference and analysis
  • Design and build scalable, efficient data analysis pipelines
  • Engage in hypothesis-driven research, rigorously testing and validating new methods and models
  • Critically evaluate results, ensuring robust models that are applicable in real-world clinical contexts beyond academic publications
  • Visualize complex datasets and create compelling narratives to communicate findings to both scientific and executive audiences

 

What we are looking for in a Senior Data Scientist :

  • PhD in a quantitative field with a strong focus on biological sciences (e.g., Applied Statistics, Biophysics, Computational Biology)
  • Postdoctoral experience is highly desirable
  • 5+ years of biotech industry experience with a proven track record of leading successful projects
  • Expertise in gene expression data analysis, including count table filtering, normalization strategies, noise quantification, differential expression analysis, and dimensionality reduction
  • Strong foundation in statistical principles and rigorous application; including, but not limited to, hypothesis testing, P-value corrections, Bayesian approaches, bootstrapping, and permutation testing
  • Extensive experience in building, training, testing, and validating machine learning and deep models, including model selection based on comparative analysis and performance metrics. Proficient in feature set development (selection, engineering, etc.) and skilled in updating and performing inference with RNA-seq-specific large language models (LLMs)
  • Ability to innovate both in applying library methods and developing algorithms from scratch
  • Experience with common data science infrastructure, including pipelines, clusters, databases, and feature stores. Direct experience with cloud platforms (AWS preferred) for scaling, deploying, and managing data workflows is a strong advantage
  • Proficient in Python and Unix/Linux environments; additional proficiency in other languages (e.g. R, Julia, Rust) is a strong plus
  • Strong coding skills across the software development lifecycle
  • Deep scientific curiosity and a solid grasp of the scientific method, hypothesis testing, and model validation

 

Why Choose R&D Partners?

As an employee, you have access to a comprehensive benefits package including:

  • Medical insurance – PPO, HMO & HSA
  • Dental & Vision insurance
  • 401k plan
  • Employee Assistance Program
  • Long-term disability
  • Weekly payroll
  • Expense reimbursement
  • Online timecard approval

 

R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.  

 

R&D Partners is an equal-opportunity employer.   

 

Company DescriptionR&D Partners is a national staffing firm focused in the areas of: Scientific, Clinical Research and Engineering. Our team offers well over 200 years of combined staffing experience providing consulting, direct hire & outsourcing solutions with our west coast offices in San Francisco, Redwood City and San Diego, CA and our east coast offices located in Harrisburg, PA and Tampa, FL.

The cornerstone of our success: a knowledgeable and experienced recruiting team.

Our life sciences recruiters, clinical research recruiters and engineering recruiters are uniquely specialized. After a detailed assessment of our clients’ needs, we can then identify appropriate candidates utilizing our established network of professionals. R&D Partners takes a proactive approach to recruiting, establishing relationships with experienced passive candidates so when the time is right, we can combine our candidates’ talents with our clients’ opportunities.Company DescriptionR&D Partners is a national staffing firm focused in the areas of: Scientific, Clinical Research and Engineering. Our team offers well over 200 years of combined staffing experience providing consulting, direct hire & outsourcing solutions with our west coast offices in San Francisco, Redwood City and San Diego, CA and our east coast offices located in Harrisburg, PA and Tampa, FL.\r
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The cornerstone of our success: a knowledgeable and experienced recruiting team.\r
\r
Our life sciences recruiters, clinical research recruiters and engineering recruiters are uniquely specialized. After a detailed assessment of our clients’ needs, we can then identify appropriate candidates utilizing our established network of professionals. R&D Partners takes a proactive approach to recruiting, establishing relationships with experienced passive candidates so when the time is right, we can combine our candidates’ talents with our clients’ opportunities.

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