Research Associate Scientist III
4 weeks ago
Location: Lexington, MA
Duration:11 Months+
Description:
- Required Education/Experience:
- Level II Master with 1-2 year | Level III Master with 4 year experience
Must haves:
- In vitro cell culture experience
- Molecular biology techniques such as RNA extraction and RT-qPCR
- Experience with vivo methodologies is a plus
Purpose:
To provide technical laboratory research effort in support of multiple projects focused on expedited evaluation and the clinical translation of therapies.
Essential Functions
• siRNA drug candidate screening, hit identification, and lead optimization
• Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; RNA extraction and RT-qPCR
• In vivo drug candidate testing (e.g., mouse dosing; sample analysis)
• Analyze data and present the results in group meetings
• Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed
• Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs
• Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research
Qualifications:
• Master’s Degree in Cell and Molecular Biology or Pharmaceutical Sciences
• 4 years of relevant drug discovery laboratory experience in industrial or academic environment is preferred
• Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR)
• Experience with in vivo methodologies is a plus (e.g., mouse handling, subcutaneous injection, intravenous injection, necropsy, sample analysis, histology)
• Experience with RNAi and in vitro screening is preferred
• Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment
• The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected
Required Education/Experience:
- Level II Master with 1-2 year
- Level III Master with 4 years’ experience
Must Haves:
- Cell culture experience and basic cell biology methodologies such as transfection
- Molecular biology techniques such as RNA extraction and RT-qPCR
- Experience with vivo methodologies is a plus
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