Research Associate, RNA Oligonucleotide Chemistry

2 months ago


Cambridge, United States Beacon Hill Life Sciences - Boston Full time
Job DescriptionJob Description

Our client is seeking an individual to work closely with the RNA Chemistry Team responsible for synthetic oligonucleotides. This individual will be involved in a complete production process for the identification, implementation & fulfillment of synthesis, purification and reaction scheme analytical characterization and method development of oligonucleotides.

 RESPONSIBILITIES:

  • Hands-on position in an oligonucleotide chemistry lab inclusive of operating, maintaining & calibrating synthesis platforms and other scientific equipment.
  • Handling automated oligo synthesizer (Expedite, Dr.Oligo, Mermaid, Akta OP-100, etc) using solid-phase.
  • Knowledge of oligonucleotide purification techniques (using Akta system) and Unicorn software.
  • Synthetic oligonucleotide method and process development participation.
  • Demonstrate basic lab competency in preparing reagents and buffers & handling chemicals.
  • Follow operating procedures and process improvement documents.
  • Documentation of results and data analysis
  • Ensure safety and product quality are paramount throughout the laboratory environment.
  • Capable of repetitive tasks and performing other duties as assigned.
  • Perform general lab-operation activities.

QUALIFICATIONS:

  • B.S. or B.A. equivalent in Organic Chemistry, Biochemistry or related field with 2+ yrs general laboratory experience or M.S. in Organic Chemistry, Biochemistry
  • Basic computer skills including MS Office Suite.
  • More experienced candidates with oligonucleotide chemistry experience will be strongly considered.
Company DescriptionBeacon Hill is an Equal Opportunity Employer that values the strength diversity brings to the workplace. Individuals with Disabilities and Protected Veterans are encouraged to apply.

If you would like to complete our voluntary self-identification form, please click here or copy and paste the following link into an open window in your browser: https://jobs.beaconhillstaffing.com/eeoc/

Completion of this form is voluntary and will not affect your opportunity for employment, or the terms or conditions of your employment. This form will be used for reporting purposes only and will be kept separate from all other records.Company DescriptionBeacon Hill is an Equal Opportunity Employer that values the strength diversity brings to the workplace. Individuals with Disabilities and Protected Veterans are encouraged to apply.\r
\r
If you would like to complete our voluntary self-identification form, please click here or copy and paste the following link into an open window in your browser: https://jobs.beaconhillstaffing.com/eeoc/\r
\r
Completion of this form is voluntary and will not affect your opportunity for employment, or the terms or conditions of your employment. This form will be used for reporting purposes only and will be kept separate from all other records.

  • Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full time

    Job OverviewWe are seeking a highly skilled Research Associate to join our RNA Chemistry Team. The successful candidate will be responsible for the synthesis, purification, and characterization of oligonucleotides.Key Responsibilities:Operate and maintain oligonucleotide synthesis platforms and other scientific equipment.Develop and implement oligonucleotide...


  • Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full time

    Job SummaryWe are seeking a highly skilled Research Associate to join our RNA Chemistry Team. The successful candidate will be responsible for the identification, implementation, and fulfillment of synthesis, purification, and reaction scheme analytical characterization and method development of oligonucleotides.Key ResponsibilitiesOperate and maintain...


  • Cambridge, United States Beacon Hill Life Sciences - Boston Full time

    Job DescriptionJob DescriptionSUMMARY:Our Client is seeking an individual to work closely with the RNA Chemistry Team responsible for synthetic oligonucleotides. This individual will be involved in a complete production process for the identification, implementation & fulfillment of synthesis, purification and reaction scheme analytical characterization and...


  • Cambridge, Massachusetts, United States Beacon Hill Life Sciences - Boston Full time

    Job SummaryWe are seeking a highly skilled Senior Scientist to join our RNA Chemistry Team. The successful candidate will be responsible for the synthesis, purification, and characterization of oligonucleotides.Key Responsibilities:Design and implement oligonucleotide synthesis and purification protocols.Operate and maintain automated oligo synthesizers and...


  • Cambridge, Massachusetts, United States Alnylam Pharmaceuticals Full time

    Job Title: Associate Scientist II, RNA SynthesisJob SummaryWe are seeking a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will design, synthesize, and purify oligonucleotides for research studies, as well as evaluate new chemical modifications for their use...


  • Cambridge, Massachusetts, United States Alnylam Pharmaceuticals Full time

    Job SummaryWe are seeking a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will design, synthesize, and purify oligonucleotides for research studies, and evaluate new chemical modifications for their use in the RNAi pathway.Key ResponsibilitiesDesign and...


  • Cambridge, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...


  • Cambridge, United States Alnylam Pharmaceuticals Full time

    Job DescriptionThis role is considered On-Site.OverviewWe are looking for a highly motivated Associate Scientist II to join our RNA Synthesis group and support RNAi-based research and drug discovery. The successful candidate will help to synthesize and purify oligonucleotides for research studies. Additionally, they will evaluate new chemical modifications...


  • Cambridge, Massachusetts, United States Simcere Full time

    Join Our Team of InnovatorsSimcere Pharmaceutical Group is a pioneering pharmaceutical company driven by cutting-edge R&D. We are committed to delivering groundbreaking medicines across core therapeutic areas, including oncology, CNS disorders, autoimmunity, and infectious diseases. Our Boston Innovation Center is dedicated to developing transformative...


  • Cambridge, Massachusetts, United States Simcere Full time

    Senior/Executive Director of CNS DiscoverySimcere Pharmaceutical Group is a pharmaceutical company driven by innovative R&D, committed to providing cutting-edge medicines for patients across core therapeutic areas, including oncology, CNS disorders, autoimmunity, and infectious diseases. Our Boston Innovation Center is dedicated to developing transformative...

  • Research Associate

    3 weeks ago


    Cambridge, Massachusetts, United States Externa Biosciences Full time

    Research Assistant - ChemistryExterna Biosciences is seeking a highly motivated Research Assistant to join our Chemistry team. As a key member of our research team, you will play a crucial role in the development and analysis of new therapeutic materials.Responsibilities:Design and execute various chemical reactions, and their analysis throughout various...

  • Director of Chemistry

    3 weeks ago


    Cambridge, Massachusetts, United States Moderna Therapeutics Full time

    About the RoleModerna Therapeutics is seeking a highly skilled Director-level chemist to lead our Discovery Chemistry group. As a key member of our team, you will be responsible for designing and synthesizing novel LNP components and oligonucleotides, driving multiple research projects across various therapeutic areas.Key ResponsibilitiesProvide strategic...

  • Research Associate

    3 weeks ago


    Cambridge, Massachusetts, United States Externa Biosciences Full time

    Research Assistant - ChemistryThe Opportunity:Externa Biosciences is seeking a highly motivated Research Assistant to join our Chemistry team. In this role, you will play a crucial part in the development and analysis of new therapeutic materials. Your responsibilities will include preparing samples, conducting HPLC and LC-MS analysis of small molecules,...


  • Cambridge, Massachusetts, United States Skills Alliance Full time

    About the RoleThis is a 6-month contract position that offers a unique opportunity to contribute to cutting-edge drug discovery projects in medicinal chemistry.We are seeking a highly motivated and passionate research associate to support several grant-funded projects in medicinal chemistry. The successful candidate will have experience with modern synthetic...


  • Cambridge, Massachusetts, United States Moderna Therapeutics Full time

    About the RoleModerna is seeking a seasoned chemist to lead our Discovery Chemistry group. As a Director-level chemist, you will be responsible for driving the design and synthesis of novel LNP components and oligonucleotides, impacting multiple research projects across various therapeutic areas.Key ResponsibilitiesProvide strategic and technical leadership...

  • Research Scientist

    4 weeks ago


    Cambridge, Massachusetts, United States GForce Life Sciences Full time

    Research and Development Associate IIIJoin GForce Life Sciences as a Research and Development Associate III and contribute to our cutting-edge research efforts in the field of biochemistry and analytical chemistry.Key Responsibilities:Design and execute in vivo PK/PD studies for therapeutic proteins, antisense oligonucleotides, viral vectors, and other...


  • Cambridge, United States Beacon Hill Life Sciences - Boston Full time

    Job DescriptionJob Description****20 hours per week***** Seeking a highly skilled and motivated Senior Research Associate /Associate Scientist to join our Nucleic Acid Process Sciences team. This is a position with a primary focus on building and executing upon processes to synthesize mRNA for our lead CRISPR/Cas9 gene editing programs. The ideal applicant...


  • Cambridge, Massachusetts, United States Moderna Full time

    About the RoleThis is a co-op internship opportunity at Moderna, a leading mRNA technology platform company. The individual will work in the chemical biology of nucleic acids and RNA biochemistry to develop Moderna's next generation building blocks for mRNA medicines. The co-op will be mentored by a Sr. Scientist and will design experiments, develop methods,...


  • Cambridge, United States GForce Life Sciences Full time

    Research and Development Associate IIIDuration: 12-month contract - potential extensionLocation: Onsite in Cambridge, MAWhat You’ll Do:• Establish and perform in vivo PK/PD studies for therapeutic proteins, antisense oligonucleotides, viral vectors, and other modalities with CNS delivery/targeting properties.• Perform in vivo immunizations to generate...


  • Cambridge, United States GForce Life Sciences Full time

    Research and Development Associate IIIDuration: 12-month contract - potential extensionLocation: Onsite in Cambridge, MAWhat You’ll Do:• Establish and perform in vivo PK/PD studies for therapeutic proteins, antisense oligonucleotides, viral vectors, and other modalities with CNS delivery/targeting properties.• Perform in vivo immunizations to generate...