Principal Automation Engineer

4 weeks ago

San Diego, California, United States Exact Sciences Full time
Help Us Change Lives

At Exact Sciences, we're revolutionizing the way the world prevents, detects, and guides treatment for cancer. We empower patients and clinicians with the clarity needed to make informed decisions when it matters most. Join our mission to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you're working to help others.

Position Overview

The Principal Automation Engineer will collaborate with a highly collaborative, cross-functional team across R&D, Operations, and Technology to develop and deploy robust laboratory automation solutions for pre-analytical sample processing, Immunoassay, and Next-Generation Sequencing based assays in support of a high-complexity laboratory-developed test. The successful candidate will help shape our strategy for automated solutions and lead a collaborative, fast-paced team to build scalable, highly integrated automation platforms that enable users to reliably and efficiently deliver timely, high-quality results in a regulated environment.

Essential Duties
  • Develop robust methods for the management and deployment of laboratory machine software to ensure concordant assay performance on hardware located in multiple sites.
  • Develop automated solutions through programming of liquid handling robotics platforms to meet the requirements of existing assay workflows.
  • Identify and address unmet automation needs through collaboration with scientists, engineers, and project teams.
  • Ensure accurate and robust automation software integration with external systems (LIMS, integrated hardware, etc.) through the development of Installation and Operational Qualification procedures.
  • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
  • Support and comply with the company's Quality Management System policies and procedures.
  • Maintain regular and reliable attendance.
  • Ability to act with an inclusion mindset and model these behaviors for the organization.
  • Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 50% of a typical working day.
  • Ability to lift up to 25 pounds for approximately 5% of a typical working day.
  • Ability to grasp with both hands; pinch with thumb and forefinger; turn with hand/arm; reach above shoulder height.
  • Ability to comply with any applicable personal protective equipment requirements.
  • Ability to use various types of laboratory equipment; including microscopes, microtomes, blades, strainers, and pipettes for extended periods of time.
  • Ability to use near vision to view samples at close range.
  • May be exposed to hazardous materials, tissue specimens, and instruments with moving parts, lasers, heating and freezing elements, and high-speed centrifugation.
  • Ability to travel 5% of working time away from work location, may include overnight/weekend travel.
Minimum Qualifications
  • Bachelor's Degree in Life Science or related field.
  • 10+ years of experience working with automated liquid handlers and associated software in a regulated environment (CLIA, CAP, ISO, etc.) or 6+ years of specialized experience with Hamilton liquid handlers.
  • High attention to detail and proven ability to effectively communicate across teams located at multiple sites.
  • Proven ability to troubleshoot technical issues in collaboration with a team of scientists.
  • Experience working in a fast-paced environment with changing priorities and demands.
  • Familiarity with Next-Generation sequencing and/or common molecular biology laboratory workflows.
  • Demonstrated ability to perform the essential duties of the position with or without accommodation.
  • Authorization to work in the United States without sponsorship.
Preferred Qualifications
  • Master's Degree in Life Science or related field.

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