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Senior Scientist RNA Process Development
2 months ago
We are seeking a highly skilled Senior Scientist to join our RNA Process Development team at Innova Solutions. As a key member of our team, you will be responsible for developing and optimizing RNA oligomer processes, working closely with cross-functional teams to drive innovation and excellence in our gene editing platform.
Key Responsibilities- Design and execute molecular cloning, biophysical, and analytical tools to develop next-generation gene edited therapies.
- Develop and optimize nucleic acid ligation reactions using splint ligation methodology.
- Design and execute ion-pairing (IP) reversed-phase (RP) chromatography methods.
- Purify oligonucleotides using chromatography and/or preparative PAGE.
- Design and evaluate the performance of new biophysical assays to identify and assess critical quality attributes (CQAs).
- Manage samples and data related to gene editing platform process development.
- Provide experimental design and executional support to team members in adjacent and related functions.
- Actively participate and support lab maintenance and continuous improvement initiatives.
- Maintain accurate and detailed laboratory notebooks and documentation.
- Summarize and present data in group meetings and contribute to group discussions.
- Author technical reports, study memos, and protocols.
- STEM degree with 2+ years of relevant industry experience.
- Experience working with, storing, and analyzing purified nucleic acids and proteins.
- Preferred qualifications include a degree in biological or chemical engineering, biochemistry, or a bio-related field, as well as experience with solid-phase oligonucleotide synthesis, bioinformatic tools, and JMP for DoE design and analysis.
Innova Solutions offers a competitive pay range of $50-$67.74 per hour, as well as a comprehensive benefits package, including medical and pharmacy coverage, dental and vision insurance, 401(k), health savings account (HSA), flexible spending account (FSA), life insurance, pet insurance, short-term and long-term disability, accident and critical illness coverage, pre-paid legal and ID theft protection, sick time, and other types of paid leaves.
