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Senior In Vivo Research Scientist

2 weeks ago


Cambridge, Massachusetts, United States GC Therapeutics Full time
Job Description

We are seeking a highly skilled and detail-oriented individual with extensive experience in animal research to join our preclinical team as a research associate. Under the supervision of a senior scientist, this candidate will support study execution for internal in vivo studies, including rodent models such as rats and mice.

About Us

GC Therapeutics is a pioneering genome-wide cell landscape exploration company that utilizes an integrated synthetic biology and AI-driven platform for cell programming. Our patent-pending pluripotent stem cell differentiation technology platform TFomeTM was developed in Professor George Church's lab and allows for the development of unique cell therapies with significantly streamlined manufacturing, improved cell quality, efficiency and speed.

Responsibilities
  • Support study execution for internal in vivo studies using rodent models such as rats and mice
  • Design, execute, and analyze in vivo studies using animal models of diseases
  • Involved in all aspects of experiments to assess GCTx's cell therapies in small animal models
Requirements
  • Bachelor's degree with 4+ years in industry, or master's degree with 2+ years
  • Proficient in mouse handling, including compound or cell administration via IV, SC, and PO routes
  • Experienced in IV, retro-orbital and saphenous vein blood collection, necropsy, and ex vivo sample preparation
  • Proficient at ex vivo tissue processing and downstream analyses using immunostaining, flow cytometry, ELISA and ddPCR
  • Comprehensive understanding of and compliance with IACUC regulations including animal care, safety, and handling regulations
  • Strong project management and organizational skills and ability to prioritize and multitask
  • Effective communication with excellent interpersonal skills
Bonus Requirements
  • Surgical experience (terminal and survival) in rodent models is a plus
  • Practical familiarity with stem cell differentiation protocols
  • Ability to conduct high-quality presentations at internal meetings
About Us Again

GC Therapeutics is committed to creating a diverse and inclusive workplace where everyone has the opportunity to thrive. We are an equal opportunity employer and welcome applicants from all backgrounds.