Director of Medicinal Chemistry

1 week ago


New York, New York, United States Otsuka Full time
Job Description:

Otsuka Pharmaceutical Company is a global healthcare leader with a commitment to innovation and excellence. As a Director of Medicinal Chemistry, you will play a key role in driving the company's research and development efforts, leveraging your expertise in medicinal chemistry to design, synthesize, and characterize novel compounds with therapeutic potential.

Key Responsibilities:
  • Provide scientific leadership in the design and development of medicinal chemistry strategies to deliver high-quality preclinical candidates.
  • Collaborate with cross-functional teams, including biology, pharmacology, and toxicology, to ensure seamless project execution.
  • Develop and implement innovative synthetic methodologies and techniques to design novel compounds with desired properties.
  • Interpret biological and ADME/PK data to inform compound design and optimization.
  • Lead interdisciplinary teams to achieve project milestones and deliver IND-ready drug candidates for First in Human (FIH) clinical testing.
Requirements:
  • PhD in medicinal chemistry and/or organic chemistry with a minimum of 7-10 years of industry experience in early discovery research.
  • Proven track record of scientific publications, patents, and delivery of clinical product candidates.
  • Strong knowledge of medicinal chemistry, pharmacology, ADME, and pharmacokinetics related to CNS-based therapeutic targets/indications.
  • Excellent communication and leadership skills, with the ability to work effectively in a fast-paced environment.
What We Offer:
  • Comprehensive medical, dental, vision, and prescription drug coverage.
  • Company-provided basic life, AD&D, short-term, and long-term disability insurance.
  • Tuition reimbursement.
  • 401(k) match.
  • PTO allotment each calendar year, paid holidays, and paid leave programs.


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