Bioinformatics Researcher

4 days ago


Brisbane, California, United States Xaira Therapeutics Full time
About the Role

We are seeking a highly skilled Bioinformatics Scientist to join our team at Xaira Therapeutics. As a member of our bioinformatics and computational biology team, you will collaborate with colleagues across the company on projects that include data system design, management, analysis, and visualization.

Key Responsibilities
  • Develop cutting-edge screening approaches and design and maintain pipelines for large-scale molecular screening data.
  • Work as a computational biologist on drug discovery program projects, collaborating on drug discovery efforts as a data analyst, and point of contact for the team's computational needs.
About You

We are looking for an enthusiastic individual who is passionate about working at the intersection of experimental and computational biology. You should have demonstrated proficiency in leveraging open-source and commercial software to analyze and present 'omics data. Familiarity with screening-related assays and the tools used in the field is also essential.

Requirements
  • Ph.D. in Bioinformatics, Computational Biology, Computer Science, Statistics, or a related field, plus 1-6 years of industry experience.
  • Experience establishing efficient pipelines for the analysis of high-throughput screening data from antibody and other large molecule drug development programs.
  • Significant experience with data processing and data mining in a biological context, including integration of multiple experimental results and databases to produce biological conclusions.
  • Ability to write high-quality analytical code both independently and as part of a team.
  • Enthusiasm and experience in software development, with demonstrated expertise in one or more commonly used programming languages such as Python, R, Go, Rust, or C/C++.
  • Experience with Linux/UNIX environments.
  • Team-oriented and highly collaborative with a hands-on approach; takes ownership of projects and advances them through both self-directed efforts as well as team engagement.
  • Demonstrated ability to design and execute computational analysis in accordance with best-in-class scientific standards and practices to ensure robust, reproducible results.
  • Understanding of statistics relevant to omics data analysis, including experimental design, handling of multiple comparisons, and mitigation of batch effects.
  • Excellent oral and written communication skills. Ability to communicate complex concepts to audiences with a wide range of backgrounds and technical familiarity.
Preferred Qualifications
  • Experience with building or maintaining scientific software.
  • Experience with analysis of a range of assay data in a drug development context, including binding (e.g., SPR), display experiments, and developability assays (e.g., viscosity and aggregation).
  • Experience with AWS or other cloud computing.
  • Experience building and maintaining Nextflow Pipelines.
Compensation

The specific compensation package for this role depends on experience, qualifications, and level. We anticipate the compensation range to be $106,000 to $167,000 per year.

Xaira Therapeutics is an equal opportunity employer. We thrive on diversity and collaboration, and we welcome candidates with diverse backgrounds and experiences.



  • Brisbane, California, United States CareDx, Inc. Full time

    Job SummaryCareDx, Inc. is seeking a skilled bioinformatician to join the Data and AI group. As a leading precision medicine solutions company, we focus on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers.The ideal candidate will be part of the DATA and AI...


  • Brisbane, California, United States Xaira Therapeutics Full time

    About the RoleWe are seeking a highly skilled computational biologist to join our bioinformatics and computational biology team. As a key member of our team, you will collaborate with colleagues in the proteomics team on projects that involve data analysis and management, proteomic platform technology development, and proteomics-related software building and...


  • Brisbane, California, United States Mammoth Biosciences Full time

    OpportunityMammoth Biosciences is seeking a highly skilled and motivated scientist to join our expanding off-target team. As a key member of our team, you will be at the forefront of advancing our understanding and optimizing Mammoth's proprietary gene-editing technology, with a particular focus on measuring and minimizing off-target effects.Key...