Scientist I
3 days ago
Collabera is seeking a highly skilled Scientist I to join our team in the development of novel in vitro complex cell models. As a key member of our research team, you will contribute to the design, development, and optimization of cell models that mimic physiological or pathological conditions, enabling the study of various biological processes and facilitating compound screening efforts.
Key Responsibilities:
- Design and optimize protocols for the efficient and reproducible differentiation of iPSCs into specific cell types.
- Characterize and validate the differentiated cells using molecular and functional assays to ensure their fidelity and functionality.
- Develop and optimize advanced cell models, including co-culture systems, organoids, or tissue-on-a-chip platforms, using iPSC-derived cells to mimic physiological or disease conditions.
- Optimize cell culture protocols, media formulations, and growth conditions to ensure the viability, functionality, and reproducibility of the developed cell models.
- Collaborate with cross-functional teams, including biologists, engineers, and data scientists, to integrate the developed cell models into larger research projects.
Requirements:
- Proven experience in iPSC maintenance, reprogramming, and differentiation techniques using various differentiation protocols.
- Proficiency in advanced cell culture techniques, including iPSC culture and differentiation, primary cell isolation, immortalized cell lines, three-dimensional (3D) cell culture systems, co-culture systems, and organoid culture systems.
- Experience in characterizing and validating differentiated cells using functional assays and molecular markers.
- Proven experience in molecular biology techniques for analysis of in vitro cell-based assays and ex vivo tissues and/or fluid (RNA isolation, qPCR, western blot, ELISA, Luminex, F/ISH, IHC, flow cytometry, etc.).
- Proficient in data analysis software suites (e.g., GraphPad PRISM, Excel, R, etc.).
About Collabera:
Collabera is a Global Digital Solutions Company providing Software Engineering Solutions for the world's most tech-forward organizations in the areas of Engineering, Cloud, and Data/AI. With its roots serving the engineering needs of the world's most recognized businesses in Technology, Financial Services, Telecom, and Healthcare, Collabera today operates across 60 locations in 11 countries, serves 30% of the Fortune 500, and has exceeded the industry growth rate by 3-4x for several years.
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