Transformational Process Engineer

2 days ago

Étreux, Hauts-de-France, United States Takeda Pharmaceutical Full time
Unlock Innovation and Deliver Transformative Therapies

At Takeda, we are a world-class R&D organization that unlocks innovation and delivers transformative therapies to patients worldwide.

About the Role:

Our team is seeking a Senior Staff Engineer - Modeling to join our dynamic and innovative team of engineers and scientists within SMPD's Process Engineering & Technology Group. As a key member of our team, you will have a strong background in chemical reaction engineering and will tackle and lead challenging problems in chemical reactions by leveraging expertise in reaction kinetics, transport phenomena, mathematical modeling, and reactor design.

You will lead and develop the scale-up and scale-down models for studying unit operations using both first-principle and data-based models. The role includes the application of process analytical technologies (PAT) combined with mathematical models (both statistical and first principle) to enhance process understanding. This will enable the effective development, optimization, scale-up, and troubleshooting of processes using in-silico approaches.

As part of the SMPD, you will report to Associate Engineering Fellow. You will collaborate with cross-functional and external partners to develop and deploy digital twins of unit operations. Partner with Automation, Manufacturing, Process Engineers, and PAT experts to develop modeling and simulation (M&S) solutions that can be deployed across the global organization for in-silico process design, development, and optimization.

You will recommend, justify and implement in silico tools and an 'in-silico first' approach to process development. Contribute to the democratization of modeling and simulation tools & results within global SMPD. Develop project or significant technical strategy and leverages technical skill(s) as a resource/expert within the department.

Recognized as a technical expert and resource within the function, you will contribute significantly and independently to project work as well as the development of platforms, which may include multiple projects within functional area. Proactively analyze technical issues and coordinate potential resolutions with project team members based on model and simulation predictions.

Review, interpret and communicate data cross functionally within pharmaceutical sciences and project teams. Significant technical responsibility for a project area/technical program within the department and potentially across Pharmaceutical sciences. Stay current in novel process modeling and simulation tools and platforms, identify process trends and defines/champions process strategy.

Influence and support initiatives related to driving scientific and technical improvement within the function and potentially cross-functionally. Identify topics for initiatives and lead local/global initiatives on behalf of senior staff. Author relevant sections of regulatory documents, validation plans, reports and peer reviewed manuscripts.

Identify vendors and build relationships to gain access to technologies as needed to deliver on pipeline and platform technology goals. Manage key vendor relationships across multiple projects as appropriate, and proactively affects resolution of issues arising at vendors. Represent Takeda and is an active member on pre-competitive collaborations with academic and industrial partners.

Minimum Requirements/Qualifications:
  • Bachelor's degree in Chemical Engineering or a related pharmaceutical science with 11+ years of relevant industry experience.
  • Maste r's degree in Chemical Engineering or a related pharmaceutical science with 9+ years of relevant industry experience.
  • Ph.D. or postdoctoral fellowship in Chemical Engineering or a related pharmaceutical science with 3+ years of relevant industry experience.
  • Strong knowledge and understanding of chemical reaction engineering and catalysis, with proven ability to demonstrate skills in these fields.
  • Strong knowledge and understanding of transport phenomena and thermodynamics.
  • Extended experience with commercially available reaction kinetic modeling software such as Ansys, ReactionLab, Dynochem, and gPROMS.
  • Extended experience with commercially available software for computational fluid dynamics (CFD) modeling such as Ansys, Star CCM+, MStar CFD.
  • Proficient in communicating and data collection from systems such as sensors, controllers, and industrial systems.
  • Experience with Matlab, Python, R, SQL, and good coding practices.
Preferred Qualifications:
  • Experience with common statistical methods, basic data science principles, and AI/ML methodologies.
  • Hands-on experience in wet lab process development.
  • Experience in multivariate analysis and Principal Component Analysis (PCA).
  • Understanding of synthetic molecule process development activities.
  • Understanding of current Good Manufacturing Practices (cGMP)
Knowledge and Skills:
  • Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems, and determine causes and possible solutions.
  • Teamwork Ability to work well in highly cross functional team environment and across global line functions.
  • Communication Skills -Able to expresses one's self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjust communication style as appropriate for the audience; timely and effectively communicates issues to supervisor; technical writing skills to support authorship of internal technical documents.
  • Organization - Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneously.
  • Knowledge Sharing - Ability to capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use.
  • Resource Management - Ability to manage one's time within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors).
  • External Involvement - Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events.
  • Technical - Subject matter expertise and knowledge of applicable process modeling and simulation tools.
TRAVEL REQUIREMENTS:

May require approximately 5-10% travel.

About Us:

We are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. We are a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, we offer stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

The estimated salary range for this position is: $133,000.00

  • Data Transformation Specialist

    6 days ago

    Étreux, Hauts-de-France, United States TechnoGen Full time

    Data Engineer Position at TechnoGenWe are seeking an experienced Data Engineer to join our team at TechnoGen. As a Data Engineer, you will play a crucial role in designing, implementing, and maintaining large-scale data systems.Job SummaryThis is a contract role that requires strong technical skills and experience with data transformation, ETL processes, and...

  • GenAI Software Engineering Director for IT Transformation

    6 days ago

    Étreux, Hauts-de-France, United States Boston Consulting Group Full time

    Transformative Role in AI-Driven IT SupportWe are seeking a visionary Global IT GenAI Software Engineer Director to spearhead our AI-driven transformation journey. This pivotal position demands expertise in designing, developing, testing, and deploying a self-service chatbot utilizing cutting-edge technologies like AWS Bedrock, industry-foundational language...

  • AI Engineering Lead for Life Sciences Transformation

    6 days ago

    Étreux, Hauts-de-France, United States Clarivate Analytics US LLC Full time

    Clarivate Analytics US LLC is seeking an AI Engineering Lead to drive innovation in its life sciences portfolio. This role will be part of the Strategy Products Organization & Startup, a global team with diverse skills and expertise.About the RoleWe are looking for a seasoned technical leader with 8+ years of industry experience and 2+ years in engineering...

  • Transformational Leader

    4 days ago

    Étreux, Hauts-de-France, United States OpenGov Full time

    About OpenGovAt OpenGov, we are driven by our mission to empower more effective and accountable government. Our cutting-edge technology has been adopted by 1,800+ governments, making us a leader in cloud software for cities, counties, and state agencies.Job OverviewWe are seeking an experienced Transformational Leader - Sr. Manager, Engineering to lead our...

  • Senior Staff Engineer

    7 days ago

    Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time

    Are you a skilled chemical engineer looking to take your career to the next level? Takeda Pharmaceuticals is seeking a Senior Staff Engineer - Process Modeling Specialist to join our team in Boston, MA.About the RoleThis exciting opportunity will have you working on the development of novel pharmaceuticals and leading cross-functional teams to design,...

  • Digital Transformation Engineer for Medical Data Registries

    7 days ago

    Étreux, Hauts-de-France, United States Astro Studios, Inc. Full time

    Astros Studios, Inc. is seeking a seasoned Senior Full Stack Engineer to join our dynamic team and play a key role in shaping the future of healthcare through innovative web application development.We believe that our diverse teams of experts combining innovative thinking and breakthrough technologies can progress further, faster. Our clients adapt and...

  • Innovative Senior Software Engineer

    1 week ago

    Étreux, Hauts-de-France, United States CVS Health Full time

    At CVS Health, our mission is to innovate healthcare solutions that make a meaningful difference in people's lives. We're seeking a highly experienced and innovative Senior Software Engineer to join our PCW Solution Engineering team.Role OverviewThe ideal candidate will collaborate with Agile teams to design, develop, test, implement, and support technical...

  • Digital Transformation Leader

    7 days ago

    Étreux, Hauts-de-France, United States WillowTree Full time

    We are seeking a highly skilled Digital Transformation Leader to join our team at WillowTree. This is a full-time role that offers a competitive salary and opportunities for growth and development.About UsWillowTree is a leading digital consultancy that partners with the world's most admired brands to orchestrate winning experiences across the customer...

  • Process Engineering Leader

    7 days ago

    Étreux, Hauts-de-France, United States Barry-Wehmiller Companies Inc Full time

    About the CompanyBW Design Group is a fully integrated architecture, engineering, construction, system integration, and consulting firm dedicated to helping our clients achieve their most critical goals. As the only firm born from a manufacturing technology company, we combine deep domain expertise in the manufacturing environment with an approach tailored...

  • Senior Infrastructure Transformation Manager

    7 days ago

    Étreux, Hauts-de-France, United States Plymouth Rock Assurance Full time

    Director of Infrastructure OperationsThe ideal candidate will lead several teams responsible for designing, engineering, and operational support of the company's hybrid cloud infrastructure. They should have recent experience leading teams that build and support infrastructure as a service using hybrid cloud solutions like Amazon Web Services and VMWare.This...

  • Strategic Business Transformation Lead

    7 days ago

    Étreux, Hauts-de-France, United States Publicis Groupe Full time

    Company OverviewPublicis Sapient is a digital transformation partner that helps established organizations achieve their future digitally-enabled state. We unlock value through a start-up mindset and modern methods, combining strategy, consulting, and customer experience with agile engineering and problem-solving creativity.Job SummaryWe are seeking a...

  • Technical Lead for AI-Driven IT Support Transformation

    7 days ago

    Étreux, Hauts-de-France, United States Boston Consulting Group Full time

    About UsBoston Consulting Group is a leading global management consulting firm that pioneers strategy consulting and innovation. We offer multiple career paths for top talent to have a real impact on business and society.Job DescriptionWe are seeking a highly skilled Technical Lead for our AI-Driven IT Support Transformation project. As a key member of the...

  • Transformational Mobility Solutions Director

    6 days ago

    Étreux, Hauts-de-France, United States HNTB Corporation Full time

    About This OpportunityHNTB Corporation is seeking a seasoned professional to lead our Emerging Mobility Senior Project Manager team. As Transformational Mobility Solutions Director, you will be responsible for overseeing multiple project teams, stakeholders, and vendors, ensuring that projects align with the company's strategic goals and objectives.Job...

  • Senior Aseptic Processing Specialist

    5 days ago

    Étreux, Hauts-de-France, United States i-Pharm GxP Full time

    Transforming Pharmaceutical Manufacturingi-Pharm GxP is a leading pharmaceutical company dedicated to delivering innovative solutions that improve lives.We are currently seeking an experienced Senior Aseptic Processing Specialist to contribute their expertise in ensuring the integrity of critical manufacturing processes in a cGMP environment.About the RoleAs...

  • Senior Process Engineer

    3 weeks ago

    Étreux, Hauts-de-France, United States Takeda Pharmaceuticals Full time

    About the RoleTakeda Pharmaceuticals is seeking a highly skilled Senior Staff Engineer to join our Process Engineering and Technology Group. As a Senior Staff Engineer - Process Modeling, you will be responsible for leading and contributing to the design, development, and optimization of manufacturing processes for synthetic molecule drug substances.Lead and...

  • Digital Transformation HR Technology Specialist

    6 days ago

    Étreux, Hauts-de-France, United States MFS Investment Management Full time

    Unlock Your Potential with MFS Investment ManagementMFS Investment Management is a leading investment management company that offers a unique culture of collaboration and innovation. As a Digital Transformation HR Technology Specialist, you will play a pivotal role in shaping the future of our organization.About the RoleWe are seeking an experienced Digital...

  • Process Engineer Expert for GMP Manufacturing

    7 days ago

    Étreux, Hauts-de-France, United States Arcadis Full time

    Arcadis is the world's leading company delivering sustainable design, engineering, and consultancy solutions for natural and built assets.We are more than 36,000 people, in over 70 countries, dedicated to improving quality of life. Everyone has an important role to play. With the power of many curious minds, together we can solve the world's most complex...

  • Transformational Full Stack Software Engineering Opportunity

    6 days ago

    Étreux, Hauts-de-France, United States Fidelity TalentSource LLC Full time

    Company OverviewFidelity Investments is a leading financial services company with a mission to strengthen the financial well-being of our clients. We provide innovative investment and technology solutions to help individuals, businesses, and institutions achieve their financial goals.About the RoleWe are seeking an experienced Senior Full Stack Software...

  • Senior Data Transformation Specialist

    6 days ago

    Étreux, Hauts-de-France, United States Mindlance Full time

    About the RoleWe are seeking a highly skilled Senior Data Transformation Specialist to join our team. In this role, you will be responsible for developing and implementing ETL processes using Talend Data Fabric toolset.

  • Digital Business Transformation Lead

    6 days ago

    Étreux, Hauts-de-France, United States Publicis Groupe Full time

    Are you a seasoned executive looking to take on a new challenge?We are seeking an experienced Digital Business Transformation Lead to join our Management Consulting practice at Publicis Sapient.About the RoleThis is an exceptional opportunity to shape and deliver goal-oriented Digital Business Transformations for our clients, leveraging your strategic advice...