Downstream Processing Team Lead

6 days ago


Chicago Illinois, United States Global Life Science Hub Full time

Job Summary:

We are seeking a highly skilled Downstream Processing Supervisor to join our team at Global Life Science Hub. As a key member of our organization, you will be responsible for leading and growing a team of professionals while executing purification processes for a wide range of mammalian-based biologics.

Key Responsibilities:

  • Lead and supervise downstream process teams in a cGMP environment, ensuring the execution of column packing, process troubleshooting, and data analysis.
  • Provide technical direction in the execution and development of the purification process, utilizing expertise in various chromatography methods.
  • Collect and evaluate operating data to conduct on-line adjustments to products, instruments, or equipment, ensuring optimal manufacturing techniques.
  • Prepare and review quality management-related documents, including deviation reports, change control documents, and investigation reports.
  • Ensure the timely execution of engineering and clinical batches, establishing operating equipment specifications and improving manufacturing techniques.
  • Collaborate with other teams and outside vendors to resolve technical issues and maintain production equipment, adhering to GMP instructions and environmental health and safety policies.
  • Coordinate the conduction of investigations and corrections for issues found during the batch execution process.

Requirements:

  • Bachelor's or Master's degree in chemical, biological, or biochemical sciences.
  • Minimum years of related experience in the biopharmaceutical industry, with a focus on GMP and aseptic manufacturing environments.
  • Experience working with AKTA Process skids or similar and familiarity with single-use manufacturing consumables, such as bags, tube sets, columns, and process manifolds.
  • Familiarity with GMP documentation and the ability to execute engineering and clinical batches.

About Us:

Global Life Science Hub is a niche Life Science headhunting firm, placing professionals across Europe and the US for a variety of Biotechnology, Pharmaceutical, and CRO companies. If you're interested in this role, please apply below. If this position doesn't interest you, please visit our website for a list of more vacancies.



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