Senior Scientist

2 days ago


MA United States Adaptimmune Full time
Job Title: Senior Scientist - Analytical Development

Adaptimmune is a leading cell therapy company with a strong presence in the UK and US. Our comprehensive capabilities and teams include preclinical research, clinical development, translational sciences, autologous and allogeneic manufacturing, and in-house commercial and corporate operations.

Our company culture is built on trust, inclusion, collaboration, and a commitment to honesty and bravery in our pursuit of transforming lives through cancer treatment.

This Senior Scientist will play a key role in the Analytical Development team, developing, optimizing, and qualifying analytical methods for early and late-stage cell therapy. The ideal candidate will have extensive experience with potency assays, molecular assays, flow cytometry, cell culture, and T cells.

Key Responsibilities:

  • Design and execute experiments, and author technical protocols and reports
  • Lead the development of assays for clinical and preclinical use
  • Design and execute qualification/validations of assays
  • Label and store samples
  • Maintain databases
  • Analyze and write up results in electronic lab notebooks
  • Prepare documentation, including study plans, SOPs, batch records, and study reports
  • Contribute to routine lab maintenance and collaborate with colleagues to progress projects

Qualifications and Experience:

  • Degree in biochemistry, chemical engineering, or related discipline
  • Substantial post-graduate experience in academic or industry settings, preferably with an MSc or PhD in a relevant scientific area
  • Extensive experience with laboratory procedures, including cell culture and flow cytometry
  • Experience with developing and troubleshooting assays and evaluating assay performance
  • Familiarity with regulatory guidelines around assay validation

Desirable:

  • Deep understanding of immunology and cell biology
  • Experience working with lentiviral vectors and primary human T cells
  • Experience with quality systems

Adaptimmune is an equal opportunities employer and welcomes applications from all qualified candidates. We believe that diversity and inclusion are essential to our success and strive to create a workplace that is inclusive and respectful of all individuals.


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