Senior Staff Engineer, Modeling

1 day ago


Lexington, Kentucky, United States Takeda Pharmaceutical Full time
About the Role

Takeda is a patient-focused company that is transforming patient care through the development of novel specialty pharmaceuticals and best-in-class patient support programs. We are seeking a Senior Staff Engineer, Modeling to join our Advanced Technologies Group within Biologics Process and Product Development.

Key Responsibilities
  • Develop and apply mechanistic modeling approaches to enhance process development and optimization of biopharmaceutical manufacturing processes.
  • Model process sustainability and economics of new or improved biopharmaceutical manufacturing platforms and integrate them into manufacturing facilities.
  • Perform multivariate process trending analysis to support development and optimization of manufacturing processes for biopharmaceuticals and bioconjugates.
  • Apply modeling approaches to process development, including model transfer learning and hybrid models.
  • Provide modeling support for biopharmaceutical process characterization activities in preparation for process validation.
  • Evaluate process and cost modeling software applications for use in biopharmaceutical development.
  • Collaborate with internal and external groups to advance process development and optimization.
Requirements
  • Ph.D. degree or M.S. degree in biochemical engineering/biotechnology or closely related fields with 3+ years (Ph.D.) or 9+ years (M.S.) of experience in modeling and bioprocess development.
  • Hands-on experience in process modeling applications, such as gProms, GoSilico, BioSolve, SIMCA, etc.
  • Additional hands-on and lab-based process and/or high-throughput development experience is preferred.
  • Familiarity with cGMPs for biopharmaceuticals and regulatory submissions.
  • Excellent communication and teamwork skills, with ability to present findings clearly to non-technical stakeholders.
  • Programming skills, such as Matlab or Python.
About Takeda

Takeda is a global, values-driven biopharmaceutical leader with a commitment to creating a diverse and inclusive workplace. We offer a comprehensive benefits package, opportunities for professional growth and development, and a collaborative work environment.

This position is currently classified as "hybrid" in accordance with Takeda's Hybrid and Remote Work policy.



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