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Senior Translational Pathologist
2 months ago
As a translational and computational pathologist, you will be part of a dynamic team driving innovation in precision medicine at GSK. Our organization is dedicated to bringing new medicines to patients in need, and we're seeking a skilled professional to join our ranks.
Key Responsibilities:- Develop and refine clinical development strategies for oncology, respiratory, immunology, and infectious diseases.
- Collaborate with biomarker scientists, companion diagnostic scientific leads, and research unit experts to enable rigorous biomarker and diagnostics plans.
- Lead clinical biomarkers assay and companion diagnostics development, oversight, and strategy, both internally and externally with CROs and partners.
- Build high-innovation clinical-grade bioassays to fulfill study program needs.
- Drive collaboration with our AI/ML organization to develop state-of-the-art computer vision digital pathology quantitative tools.
- Review protocols, amendments, and revisions, and participate in study governance to ensure efficient and successful study execution.
- Support companion diagnostics across the business, interface with regulatory authorities, and prepare submission documentation.
- Participate in clinical trials advisory boards, seek input from key opinion leaders, and deliver concise recommendations to study teams.
- Interface with external KOLs, clinical trial sites, technology vendors, and business development partners.
- MD or DO degree from an accredited training program and board certification (or local equivalent).
- Residency Anatomic Pathology (AP) or combined Anatomic Pathology/Clinical Pathology (AP/CP) training and American Board of Pathology (ABP) board certification (or equivalent).
- Surgical Pathology subspecialty training and board certification.
- Skills in laboratory medicine, including molecular genetic pathology, flow cytometry, assay development, and validation.
- Experience in pathophysiology of human diseases and clinical practice.
- 5+ years of relevant clinical work experience, including medical education in hospital, outpatient clinic, and other medical environments.
- 2+ years of additional postgraduate clinical work experience.
- Experience in diagnostic pathology and laboratory medicine, including image analysis tools and whole slide image review.
- Data and science experience, including basic statistics, quality assurance, and experimental controls.
- Master's level degree (MS, MEng, MPH) and/or Ph.D. in a related field with bench wet-lab experience.
- Pharmaceutical industry experience in translational biomarkers, clinical development, field, or discovery.
- Ability to interface with quality teams across the organization.
- Immunohistochemistry, molecular/genomics/NGS, and flow cytometry assay validation, review, creation, optimization, and data reporting.
- Track record of regulatory engagements.
- Clinical trials matrix team experience.
- Track record of companion diagnostics development in IHC, molecular genetic pathology, flow, or other areas.
- Additional board certification in other pathology subspecialties.
- Experience in digital pathology, image analysis, data science, computer programming, and related investigative methods.
- Experience in clinical and research laboratory setup, leadership, public speaking, education of histo-technologists, trainees, allied health professionals, inspection, and quality monitoring in anatomic pathology.
- Clinical trials support, protocol and study documentation review/authorship, contract research organization interfacing, multinational matrix influencing skills.
We offer a comprehensive benefits program and a dynamic work environment that fosters innovation and collaboration. If you're passionate about precision medicine and want to make a meaningful impact, we encourage you to apply.
