Upstream and Downstream Specialist

2 days ago


San Diego, California, United States Adcentrx Therapeutics Full time

**Job Description:**

We are looking for a highly skilled **Principal Scientist/Associate Director Antibody Process Development** to join our team at Adcentrx Therapeutics.

This role involves leading the development of novel targeted biotherapeutics through upstream and downstream process development, medium development, feeding strategies, process parameter optimization, chromatography, and scale-up for large-scale production.

The ideal candidate will have hands-on experience with CHO and other mammalian cells for mAb or recombinant protein production, as well as previous experience in cell culture scale-up, tech transfer, and GMP.

Key Responsibilities:

  • Develop and implement processes for antibody manufacture.
  • Lead technology transfer to third parties, including partners and CMO.
  • Author development reports and CMC sections for regulatory submissions.

Qualifications:

  • Ph.D. with 4+ years of industry experience or MS with 8+ years of industry experience in Biochemical Engineering, Chemical Engineering, Biochemistry, or related field.
  • Hands-on experience with CHO and other mammalian cells for mAb or recombinant protein production.
  • Previous experience in cell culture scale-up, tech transfer.
  • GMP experience.

What We Offer:

  • A competitive total compensation package.
  • A comprehensive benefits program, including medical, vision, and dental coverage, 401(k), company-paid holidays, and stock options.

Adcentrx Therapeutics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.



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