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Senior Principal Chemist

2 months ago

Marquand, Missouri, United States Eli Lilly Full time
About the Role

We are seeking a highly skilled and experienced Senior Principal Chemist to join our Bioproduct Research and Development (BR&D) organization at Eli Lilly. As a key member of our team, you will play a critical role in delivering new medicines to patients through the development and commercialization of insulins, peptides, oligonucleotides, monoclonal antibodies, novel therapeutic proteins, and gene therapy systems.

Key Responsibilities
  • Enable the design, development, and implementation of analytical methodologies for the characterization and analysis of cell and gene therapy products.
  • Contribute to the establishment of robust control strategies through generation of data, development of analytical methods, design and execution of stability strategies.
  • Engage with scientists across development and manufacturing as well as through collaboration with external development partners to design and implement control strategies for projects at various stages of development.
  • Responsible for evaluating and/or implementing new analytical technologies/methods to advance Lilly's current analytical capabilities.
  • Spearhead new initiatives to improve existing scientific processes within the organization and across the company.
  • Identify and exploit new scientific concepts, strong problem-solving skills, and be self-motivated to contribute across multiple projects.
  • Demonstrate strong written and verbal communication skills to speak to both technical and business-related implications of your work.
  • May supervise other BS/MS analytical scientists supporting BR&D analytical development.
Requirements
  • MS with 3+ years of drug development experience, BS with 8+ years of drug development experience or PhD with 0-5 years of experience.
Preferred Qualifications
  • Experience with analytical control strategy development from pre-FHD to commercial launch.
  • Demonstrated proficiency with drug development for cell and gene therapy products.
  • Experience with chromatographic separations (reversed phase chromatography, ion exchange chromatography, size exclusion chromatography), capillary electrophoresis, spectroscopic methods, and other methods for the analysis of cell and gene therapy products.
  • Knowledge of ddPCR and ELISA based methods for analysis of cell and gene therapy products.
  • Effective oral and written communication skills.
  • Demonstration of scientific and people leadership skills.
  • Demonstrate proficiency in multiple modes of chromatography, mass spectrometry, optical spectroscopy, instrument engineering, or other analytical technologies.
  • Experience with data interpretation, including the application of chemometrics, multivariate modeling, and other data manipulation tools.
  • Learning agility and demonstrated ability to apply technical knowledge to improve the understanding of chemical systems or improve analytical techniques.
  • Ability to balance multiple activities, prioritize evolving project needs, and handle ambiguity.
  • Must be able to work productively in an interdisciplinary team environment.
Additional Information
  • Travel: 0 to 15%
  • Potential exposure to chemicals, allergens, and loud noises.
  • Position Local: Indianapolis, IN; Lilly Technology Center-North (LTC-N)