Research Scientist
18 hours ago
Kyowa Kirin is a global pharmaceutical company that applies cutting-edge biotechnologies to discover and deliver innovative medicines in four key areas: bone and mineral disorders, intractable hematologic diseases, hematology oncology, and rare diseases.
We are seeking a highly motivated Research Scientist I/II to support our cell therapy pipeline programs in a collaborative environment. This role will play a critical part in developing next-generation cell therapy programs from drug discovery to IND.
Key Responsibilities:- Design, optimize, and scale processes for pipeline projects
- Conduct experiments and analyze data to support process improvements
- Collaborate with R&D, quality assurance, and manufacturing teams to ensure seamless process integration
- Maintain compliance with regulatory guidelines and internal standards
- Identify opportunities for automation and process enhancement
- Troubleshoot and resolve process-related issues in a timely manner
- Provide support for technology transfer to CMC/CRO/CDMO
- Ph.D. in Biological Sciences, Immunology, Molecular Biology, Biochemistry, or a closely related discipline
- Minimum five (5) years' biotech/pharma industry or academia experience in cell therapy process development
- Extensive knowledge of cell therapy concepts and exploration, including in vitro and in vivo study experience
- Hands-on experience in developing and characterizing cell therapy products, including HSC, iPSC, and/or CAR-T
- Familiarity with synthetic biology concepts and approaches, including gene and/or base editing
- Understanding of relevant Regulatory guidelines (GMP, ISO, ICH) is preferred
- Familiarity with FDA regulatory requirements for Cell Therapy is desired
- Experience with handling, culturing, and differentiation of human stem cells to various types of immune cells is highly preferred
- Experience with development of potency assays and other related QC release assays is highly desired
- Strong knowledge of Immunology, Hematology, and/or Cancer Biology
- Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities
- Excellent written, verbal, and listening communication skills: articulate and effective communicator and presenter
- Self-motivating and creative, able to work within a team and collaborate proficiently with colleagues to achieve program goals
- Demonstrated familiarity with flow cytometry and other immunostaining assays
- Experience with gene modification and genome editing technologies
- Experience in handling viral vectors
- Stem cell culturing and differentiation into immune cells
- Ability to manage a high-volume workload and adapt to workload based upon changing priorities
- Solid proficiency in Microsoft Office Suite (Excel, Word, Outlook, etc.)
Annualized base salary ranges from $105,000 - $135,000 plus short-term incentive bonus; actual salaries will vary and may be above or below this range commensurate with various factors including but not limited to experience, education, training, and merit.
Kyowa Kirin is an equal opportunity employer and welcomes applications from diverse candidates. We are committed to creating an inclusive work environment that values diversity, equity, and inclusion.
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