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Senior Bioanalytical Scientist
2 months ago
Position Overview
The Bioanalytical Chemistry team at Integrated Resources is seeking a skilled scientist with expertise in LC-MS based pharmacokinetics and biomarker assay development. This role is crucial for enhancing our bioanalytical strategies and optimizing our innovative platforms.
Key Responsibilities
- Design and refine advanced LC-MS analytical methodologies for bioanalysis across various molecular formats, including small molecules and proteins.
- Implement cutting-edge high-resolution mass spectrometry techniques for metabolite profiling and identification.
- Conduct biomarker analysis using LC-MS techniques as needed.
- Analyze complex LC-MS data sets and effectively communicate findings to project teams.
- Maintain comprehensive records of experimental procedures and results in electronic laboratory notebooks.
- Contribute to team knowledge through ongoing literature review and collaborative discussions.
- Oversee the maintenance and troubleshooting of laboratory instruments, including HPLC and LC-MS systems.
Qualifications
- Required:
- PhD or Master's degree in pharmaceutical sciences, analytical chemistry, biochemistry, or related fields, with relevant industry or academic experience.
- 3-5 years of relevant experience with a PhD or 5+ years with a Master's degree.
- Proven laboratory skills in biological sample extraction and quantitative/qualitative mass spectrometry.
- Experience in bioanalysis of various molecular formats, including small molecules and proteins.
- Self-driven with a proactive approach to research.
- Strong written and verbal communication skills.
- Able to excel in a fast-paced, multidisciplinary research environment.
Preferred Qualifications
- Experience with LC-MS-based ADME and bioanalytical assays.
- Familiarity with mass spectrometry data acquisition software such as Analyst and Xcalibur.
- Knowledge of bioanalytical method validation guidelines.
