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Associate Research Scientist

2 months ago


Seattle, Washington, United States Innova Solutions Full time
Job Summary

Innova Solutions is seeking a highly motivated and experienced Associate Research Scientist to join our Gene Delivery and Editing Process Development team. As a key member of our team, you will be responsible for supporting the development of lipid nanoparticles (LNPs) for gene editing capabilities.

Key Responsibilities
  • Execute and troubleshoot process development experiments supporting LNP production and purification.
  • Assist in the design of experiments and interpretation of data relating to LNP production and purification.
  • Manage the flow of samples and data and perform analyses.
  • Optimize workflows for assessing new modes of production and purification.
  • Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities.
  • Actively participate and support lab maintenance and continuous improvement initiatives.
  • Maintain accurate and detailed laboratory notebook and documentation.
  • Summarize and present data in group meetings and contribute to group discussions and team strategy.
  • Author technical reports and study memos.
Requirements
  • Experience with production and purification of LNPs or molecule of similar nature.
  • Bachelor's Degree in biological or chemical engineering, biochemistry, or bio-related field.
  • Experience with handling of nucleic acids.
  • Experience with LNP characterization techniques (HPLC, DLS, MALs, NTA, etc.).
  • Experience downstream purification of biological molecules (AKTA, chromatography, TFF, viral filtration, etc.).
  • Experience with development of continuous processes and implementation process-analytical technologies (PATs).
  • Experience with microfluidic technologies.
  • Experience in the development of other gene delivery or editing materials (e.g. adeno-, retro-, lenti-, RNPs, Cas, mRNA, etc.).
  • Demonstrated and extensive experience with TFF and sterile filtration of biological molecules.
  • Experience with JMP for DoE design and analyses.