Senior Research Scientist, Bioanalytical Chemistry Expert

4 weeks ago


Chicago, Illinois, United States TalentCraft Full time
Senior Scientist, Bioanalytical Chemistry

TalentCraft is partnering with a pharmaceutical company in the Chicago area to find a highly skilled Senior Scientist specializing in Bioanalytical Chemistry. This pivotal role involves driving innovation in understanding drug behavior within biological systems by developing and applying advanced bioanalytical techniques.

Key Responsibilities:

  • Develop and validate bioanalytical methods for quantitative analysis of biological samples, ensuring accuracy, sensitivity, and reproducibility.
  • Apply advanced mass spectrometry techniques to support pharmacokinetic, pharmacodynamic, and toxicological studies.
  • Design and execute experiments, analyzing complex data to provide insights into drug candidate pharmacokinetics and metabolism.
  • Collaborate with cross-functional teams, including pharmacologists, toxicologists, and medicinal chemists, to integrate bioanalytical data into drug development.
  • Oversee the operation and maintenance of bioanalytical instruments, ensuring optimal performance for high-throughput analyses.

Required Skills and Experience:

  • M.S. or Ph.D. in Bioanalytical Chemistry, Analytical Chemistry, or a related field.
  • For Ph.D. candidates: 5+ years of postdoctoral experience in bioanalytical chemistry.
  • For M.S. candidates: 10+ years of experience in bioanalytical chemistry; pharmaceutical or biotech industry experience strongly preferred.
  • Extensive experience with LC/MS-MS and other high-throughput analytical techniques for analyzing biological samples in complex matrices (e.g., serum, tissue, tumor).
  • Experience with bottom-up proteomics workflows and analysis of peptide-based modalities is highly preferred.
  • Proven track record in developing and validating bioanalytical methods for drug development.
  • Strong collaboration skills and the ability to work within multidisciplinary teams.
  • Excellent written and verbal communication skills, with a focus on presenting complex scientific data.


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