Senior Research Scientist in Molecular Ophthalmology

3 weeks ago


Philadelphia, Pennsylvania, United States University of Pennsylvania Full time

As a Senior Research Scientist at the University of Pennsylvania, you will play a key role in advancing our understanding of OPA3-mediated ophthalmic diseases. Your primary responsibility will be to conduct cutting-edge research on disease modeling and therapy development, leveraging your expertise in genome, transcriptome, proteome, and metabolome studies.

We are seeking a highly skilled researcher with a strong background in CRISPR technology, iPSC disease-models, and gene therapy interventions. The successful candidate will have experience in developing delivery platforms, such as LNP- or AAV-mediated, and a proven track record of publishing manuscripts in top-tier peer-reviewed journals.

Your duties will include:

  • Designing and executing genome-scale studies to identify key outcome measures for therapeutic efficacy
  • Screening commercially available and new drugs in diseased cell models using high-throughput techniques
  • Developing and implementing CRISPR-based gene editing approaches to generate iPSC disease models
  • Collaborating with colleagues to develop novel gene therapy interventions and delivery platforms
  • Presenting research findings at national and international conferences and publishing in top-tier scientific journals

The University of Pennsylvania offers a dynamic and inclusive research environment with a strong commitment to diversity and equal opportunity. As a member of our team, you will have access to state-of-the-art facilities, cutting-edge technologies, and opportunities for professional growth and development.

We offer a competitive salary range of $90,000 - $110,000 per year, commensurate with experience, plus a comprehensive benefits package that includes health insurance, retirement savings, and paid time off. If you are a motivated and talented researcher looking for a challenging and rewarding career opportunity, we encourage you to apply.



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