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Lab Manager

2 months ago


St Louis, Missouri, United States Harris-Stowe State University Full time
Job Summary

Harris-Stowe State University is seeking a highly skilled and detail-oriented Lab Manager to join our research team studying the effects of light pollution on pregnancy, with a focus on generational and gestational impacts.

This is a limited-time position funded by a grant. The successful candidate will support laboratory operations, conduct experiments, and ensure the smooth functioning of daily lab activities.

Key Responsibilities
  • Train and organize undergraduate researchers.
  • Stay abreast of industry trends, emerging technologies, and best practices in neurobiology.
  • Perform routine laboratory tasks, including preparation of solutions, reagents, and media.
  • Order lab supplies.
  • Organize Laboratory meetings and presentations.
  • Lead the planning, design, and launch of new grant-related protocols and procedures in line with industry standards.
  • Conduct experiments related to light pollution effects on pregnancy, under the guidance of senior researchers.
  • Record, store, and manage experimental data accurately.
  • Ensure compliance with safety and regulatory guidelines.
  • Maintain a clean and organized lab environment.
  • Maintain and calibrate laboratory equipment.
  • Collect, process, and analyze biological samples (e.g., blood, brain, and uterine tissue).
Requirements
  • A minimum of a Bachelor's degree in Neuroscience, Biology, Chemistry, or a related field.
  • Prior neuroscience laboratory experience preferred.
  • Proficiency in basic laboratory techniques and equipment.
  • Strong attention to detail and organizational skills.
  • Ability to work independently and as part of a team.
  • Excellent communication skills.
Preferred Qualifications
  • A Master's degree in Neuroscience or Biology.
Knowledge, Skills, and Abilities
  • Deep understanding of neural mechanisms related to reproductive physiology, including hormonal regulation, brain regions like the hypothalamus, and neuroendocrine pathways.
  • Expertise in reproductive systems, including hormonal cycles, fertility, pregnancy, and mother-infant interactions.
  • Strong knowledge of biological rhythms (circadian rhythms) and how light exposure affects these rhythms, especially in relation to reproduction.
  • Insight into the effects of artificial light at night (ALAN) on living organisms, particularly its impact on sleep, circadian rhythms, and reproductive health.
  • Proficiency in designing experiments, data collection, and statistical analysis in neuroscience, reproductive physiology, and environmental studies.
  • Knowledge of ethical guidelines for animal care in neuroscience and reproductive research, including working with Institutional Animal Care and Use Committees (IACUC) and human subjects, if applicable.
  • Skills in techniques such as PCR, Western blotting, ELISA, immunohistochemistry, and gene expression analysis to study molecular changes in response to light pollution and reproductive cues.
  • Expertise in microscopy (confocal, fluorescent) and possibly in vivo imaging methods like fMRI or calcium imaging to visualize neural circuits and reproductive organs in response to environmental light changes.
  • Proficiency in working with animal models, especially rodents, for conducting reproductive and neuroscience experiments, including knowledge of mating cycles, estrous monitoring, and light exposure manipulation.
  • Strong skills in statistical software (SPSS, R, Python) for analyzing experimental data.
  • Ability to design and perform behavioral tests related to reproductive success, mating behaviors, circadian rhythms, and stress responses in animal models.
  • Skills in setting up and controlling light conditions (intensity, wavelength, duration) for experiments investigating light pollution and its effects on physiology.
  • Strong ability to collaborate with environmental scientists, endocrinologists, and chrono biologists, as well as manage lab teams and coordinate interdisciplinary research.
  • Ability to generate hypotheses related to how light pollution impacts reproductive physiology and design experiments that effectively address these questions.
  • Precision in experimental design, data collection, and data analysis to ensure reproducibility and reliability of research findings.
  • Ability to clearly communicate complex scientific concepts, both in writing (research papers, grants) and verbally (conferences, lab meetings).
  • Ability to adapt and innovate laboratory methods to study interactions between light pollution, reproductive physiology, and neural function.
  • Strong abilities in writing research proposals to secure funding for the lab.
  • Capacity to mentor students and junior researchers, teaching them complex neuroscience and physiology techniques, and fostering an environment of collaboration and learning.