Neuroscience Investigator

6 days ago

Bethesda, Maryland, United States Astrix Full time
Senior Scientist Position

Salary:

$70,000 - $90,000 per year

Job Description:

Astrix seeks an experienced Senior Scientist to join our team for a one-year contract position with benefits and paid time off.

This exciting opportunity involves conducting research on neurodevelopment and neuroprotection using primary cells in culture and in vivo mouse models.

  • Conduct research on neurodevelopment and neuroprotection.
  • Design and perform experiments: maintain stem cells, primary neurons, and plan all details to understand the role of GPCR ligands in neurogenesis/stem cell differentiation, neurite growth, synaptogenesis, signaling/gene expression, and recovery in mouse models of spinal cord injury.

Analyze data, summarize, and prepare reports for presentation and/or publication. Share technical knowledge with staff and trainees on biochemical and cell biological experiments, including reporter assays, cell culture, biochemical, immunocytochemical, molecular biological, and confocal microscopic imaging procedures.

Key Responsibilities:
  • Prepare purchase request forms for laboratory supplies.
  • Assist junior lab members in basic laboratory procedures and safe procedures.
  • Provide support for common laboratory equipment.
  • Perform genotyping of mouse lines.
  • Maintain mouse lines.
  • Build experimental setups necessary for ongoing research.
Requirements:
  • Master's degree in biochemistry, cell biology, or neuroscience.
  • Two years of experience in maintaining and primary neural cell culture and differentiation into neurons.
  • Experience in mouse surgery including spinal cord injury.
  • Two years of experience in immunocytochemistry and confocal microscopy (experience with Zeiss microscopy is preferred).
  • Demonstrated expertise in cell-based in vitro assays; qPCR, western blotting, cAMP assay, calcium assay, synaptogenesis.
  • Experience in FACS analysis.
  • Able to independently analyze data, troubleshoot, and solve problems.
  • Excellent record keeping, ability to follow precise steps in a protocol.
  • Experience with Microsoft office like Excel, Graph Pad prism for data analysis is preferred.
  • Ability to work independently.

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