Research Scientist

3 weeks ago


San Francisco, California, United States University of California Full time

Overview

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The University of California, San Francisco (UCSF) seeks a highly skilled and detail-oriented Staff Research Associate to join our team in the Department of Neurological Surgery. As a Staff Research Associate, you will play a critical role in supporting the UCSF Brain Tumor Center by procuring brain tumor specimens from surgeries, providing histology services for both research and clinical purposes, and maintaining our 46-year-old repository.

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Estimated Salary Range: $28.04 - $45.09 per hour (dependent on experience)

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About the Job

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  • Collecting, processing, and archiving neurological tumor tissues and blood samples for use by Brain Tumor Center investigators and for NeuroOncology clinical trials
  • Data entry of patient and biospecimen information into Tissue Bank databases and sample tracking system
  • Operating and maintaining core equipment: automatic tissue processor, Ventana automated immunostainers, liquid nitrogen storage systems, microtome, and cryostat
  • Processing histology requests that entail the generation of paraffin or frozen sections
  • DNA isolation from various sources of tissue or blood
  • Retaing and verifying consents
  • Archiving sample retrieval (both frozen and paraffin) for histology or clinical requests
  • Maintaining human and animal cell cultures to ensure adequate inventory in the Tissue Bank for distribution
  • Performing immunohistochemical staining for major Core projects as well as other individual investigators
  • Maintaining antibody inventory, tracking, and updating protocol changes, organizing control slides to assure results and best utilize resources
  • Performing and documenting clinical IHC work: test slides, controls, instrument logs, and pathologist review sheets as required by CLIA standards
  • Quantifying MIB-1 labeling index to predict tumor cell proliferation and invasiveness
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Required Qualifications:

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  • Bachelor's degree in Biology, Chemistry, Anatomy, or related science with knowledge of or experience with basic techniques or methods required by the position
  • One or more years of recent, directly related work experience utilizing the techniques or methods required by the position
  • Competency to operate the tissue processor and dispose of hazardous reagents
  • Experience managing large amounts of data for special projects


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