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Pediatric Hematology Oncology Project Scientist

1 month ago


Montebello, California, United States InsideHigherEd Full time
Job Title: Pediatric Hematology Oncology Project Scientist Job Summary: The Jonas Lab in the Department of Pediatrics, David Geffen School of Medicine & California NanoSystems Institute at UCLA is seeking a highly motivated project scientist interested in pursuing interdisciplinary research at the interface of nanoscience and regenerative medicine. Responsibilities: * Establish rapid, safe, cost-effective, and efficient intracellular delivery methods for genes and genome-editing machinery. * Design and apply nanocarrier systems to enable cystic fibrosis gene therapies. * Develop microfluidic liquid biopsy technologies for monitoring treatment response to pediatric sarcomas and other childhood malignancies. * Apply rapid prototyping approaches to fabricate three-dimensionally printed tools for organoid development & toxicity screening of electronic cigarette/vaping products. Qualifications: * PhD, MD/PhD, or equivalent in Bioengineering, Materials Science, Chemistry, Mechanical Engineering, Physics, Electrical Engineering, Molecular Biology or related life science fields of study. * Background in nanoparticle synthesis & characterization and mRNA therapeutics. * Solid understanding and experience in micro/nanofabrication techniques, microfluidic devices, three-dimensional printing, device design and characterization. * Experience in cell culture, cell biology & molecular biology, immunofluorescence/flow cytometry, next generation sequencing techniques, gene editing methods, and biochemical techniques desired. * Ability to multitask and quickly adapt to new research challenges. * Excellent communication skills and ability to work in a diverse, interdisciplinary research environment and to interact with computational and experimental scientists. Skills: * Experience with micro/nanofabrication techniques, including photolithography and three-dimensional printing for rapid prototyping and application of microfluidic systems. * Experience in the design of computer models/simulations for prototyping of project-specific devices. * Experience in nanoparticle synthesis and characterization (e.g., lipid nanoparticles, polymeric, plasmonic nanomaterials). * Experience with cell culture, transfection, immunofluorescence/flow cytometry, and biochemical and molecular biology techniques. * Comfortable working with human primary cell types including hematopoietic stem cells, immune cells, or pluripotent stem cells. Duties and Responsibilities: * Ability to work and lead more independently and multitask projects more extensively. * Leadership and coordination of project activities and collaborative efforts. * Oversee development of technology platforms for cellular therapy manufacturing, nanoparticle vehicles, organoids, and/or liquid biopsy diagnostic tests and characterization of cell products resulting from this work. * Ability to multitask and contribute to and oversee multiple collaborative projects efficiently and effectively. * Supervision, mentorship, and teaching of undergraduate, graduate, and medical students, new postdoctoral trainees, and staff research associates in the lab. How to Apply: To apply, please visit: https://recruit.apo.ucla.edu/JPF09392