Pharmacometrics Director

{"h1": "Pharmacometrics Director Job Opportunity at Vir Biotechnology, Inc.", "p": "We are seeking a highly skilled Pharmacometrics Director to lead our pharmacometrics strategy across therapeutic areas and programs, from early clinical development to market application and commercialization. The successful candidate will join the Clinical Pharmacology department and report to the VP of Clinical Pharmacology.", "ul": [{"li": "Develop and implement model-informed drug development (MIDD) plans across projects and disease areas to optimize prospective studies and inform drug development strategy and project decision-making."}, {"li": "Conduct modeling and simulations activities for programs across multiple stages of development, from pre-IND through post-marketing."}, {"li": "Present modeling and simulation data as a technical pharmacometrics expert on cross-functional project sub-teams."}, {"li": "Identify opportunities where modeling and simulation can promote the understanding of pharmacological activity, efficacy, and safety."}, {"li": "Provide support and help develop our quantitative methodology, pharmacometrics tools, software, hardware, and related business processes."}], "h2": "Requirements", "ul": [{"li": "PhD with at least 10 years of experience OR MS degree with at least 13 years of experience"}, {"li": "Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, mathematics, statistics, or biostatistics"}, {"li": "Experience with quantitative modeling, including performing population PK/PKPD analyses using standard pharmacometric software (e.g., NONMEM, R, Monolix, Phoenix) for protein therapeutics (e.g., mAbs, siRNA) and small molecule therapeutics"}, {"li": "Experience managing MIDD regulatory strategies together with clinical pharmacology project leads to achieve desired outcomes"}, {"li": "Experience with quantitative systems pharmacology (QSP) and physiologically based pharmacokinetic (PBPK) modeling"}, {"li": "Experience with clinical pharmacology studies to support intrinsic/extrinsic factors and the ability to author and defend pharmacometrics components of regulatory filings"}, {"li": "Lead modeling and simulations activities with external CROs"}, {"li": "Mentor junior staff within Clinical Pharmacology"}], "h2": "What We Offer", "p": "The expected salary range for this position is $194,500 to $284,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors. Vir's compensation and benefits are aligned with the current market and commensurate with the person's experience and qualifications. All full-time employees receive a package that includes: compensation, bonus, and equity as well as many other Vir benefits and perks such as health, dental, vision, life, and disability insurance benefits, non-accrual paid time off, company shut down for holidays, commuter benefits, child care reimbursement, education reimbursement, 401K match, and lunch for all onsite employees.", "h3": "About Vir Biotechnology, Inc.", "p": "Vir Biotechnology, Inc. is a biotechnology company focused on developing innovative treatments for infectious diseases and cancer. We are committed to advancing the field of pharmacometrics and improving patient outcomes through our cutting-edge research and development efforts.", "h3": "How to Apply", "p": "If you are a motivated and experienced pharmacometrician looking for a new challenge, please submit your application, including your resume and a cover letter, to [insert contact information]."}