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Microbial Pathogen Research Associate

2 months ago

Columbus Ohio, United States Nationwide Children's Hospital Full time

Position Overview:
We are in search of a dedicated and detail-oriented recent graduate who possesses some laboratory research experience.

The successful candidate will primarily engage in hands-on laboratory work, while also gaining insights into various scientific disciplines, including scientific writing, practical methodologies, data interpretation, critical thinking, literature evaluation, and presentation skills.

This role entails managing all facets of an independent research project under the guidance of a postdoctoral researcher and Dr. King. Our investigations center on bacteria belonging to the Streptococcus genus.

These bacterial species are responsible for numerous human illnesses, such as pneumonia, bacteremia, otitis media, and endocarditis, significantly contributing to global morbidity and mortality rates.

To develop more effective vaccines and therapeutic strategies, a deeper comprehension of the pathogenic mechanisms employed by these bacteria is essential.

Glycans are present on all host surfaces and many host molecules, playing a pivotal role in the disease process.

Dr.

King's lab focuses on understanding how alpha-hemolytic streptococci interact with and modify host glycans, and how these interactions influence colonization and disease progression.

Current research efforts are directed towards examining how the endocarditis-causing pathogen S. oralis interacts with glycans in the oral cavity and heart, contributing to disease manifestation.

Why Choose Nationwide Children's Hospital?
Upon entering our facility, you will sense the difference. Engaging with our patient families, you will feel the commitment. Conversations with our staff will inspire you to become part of our mission. Welcome to Nationwide Children's Hospital, where passion aligns with purpose.

We are committed to integrating Diversity, Equity, and Inclusion into our core values and practices. We strive to cultivate, maintain, and enhance an inclusive and equitable environment.

We are looking for individuals who embody these values and are eager to share their experiences and contributions to our collective mission.

Our team comprises 14,000 dedicated professionals.

It takes every one of us to enhance the lives of the children we serve, as well as those around the globe whom we may never meet.

Children who lead healthier, more fulfilling lives due to the knowledge we impart.

We recognize that a Collaborative Culture is essential to fulfilling our promise of delivering exceptional, innovative care and fostering groundbreaking discoveries through research.

Anywhere.

Ask any member of the Nationwide Children's team about their role, and they will express that it is more than just a job. It is a calling—a chance to utilize and develop your talents to make a meaningful impact. Here, our sole purpose is to assist children everywhere.

Nationwide Children's Hospital. A source of pride.

Key Responsibilities:

PRIMARY DUTIES AND RESPONSIBILITIES
Conduct research experiments autonomously or with minimal supervision, adhering to protocols established by the principal investigator. These experiments may involve laboratory animals or human subjects and could require evening and/or weekend work.

Prepare and evaluate substrates, perform assays, and cultivate tissues for research purposes as needed. Collect blood, urine, and other samples as required. Such tasks may be performed independently and may necessitate evening and weekend hours.

Ensure the precision of laboratory analytical procedures as dictated by specific research projects.


Gather and manage experimental data and patient information; maintain accurate daily logs of experiments, including methodologies, results, and conclusions.

Analyze data results with guidance from the principal investigator.

Assist the principal investigator in drafting scientific publications and grant applications.

Recommend enhancements or alternatives to laboratory analytical procedures. Implement such improvements or new methods with input from the principal investigator.


Order necessary supplies for research; manage inventory of equipment and materials; ensure that research apparatus is functioning properly.


Collaborate in preparing research budgets and monitor expenditures to ensure studies remain within financial constraints.

Instruct other laboratory personnel and students in standard methods, practices, procedures, and equipment usage.

Maintain a tidy work environment and perform general laboratory upkeep. Adhere to appropriate safety protocols and procedures.

Perform other related duties as assigned.

Qualifications:
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED


Bachelor of Science degree with two to three years of laboratory research experience, or relevant certification and experience may be considered in lieu of formal education.

Laboratory experience is preferred. Coursework in anatomy, physiology, statistics, relevant research methodologies, and radiation is desirable.

MINIMUM PHYSICAL REQUIREMENTS


Percent of time spent on: 50% Preparing test substrates, conducting assays, preparing cultures 25% Analyzing data results with PI 11% Miscellaneous paperwork associated with research 10% Ordering supplies 02% Budget preparation 02% Instructing other lab personnel Minimum physical requirements: 100% Kneeling / reaching 100% Finger dexterity 100% Talking / hearing / seeing 33% Lifting / carrying weight 0-20 pounds for 1-5 minutes The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification.

It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision.

EOE M/F/Disability/Vet