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Principal Research Associate in Cell Therapy

2 months ago


California, United States Hydrogen Group Full time

Position Overview:

Key Responsibilities:

  • Design and validate flow cytometry-based assays aimed at comprehensive characterization of immune cell biology and functionality, including the development of Standard Operating Procedures (SOPs) and detailed technical documentation.
  • Collaborate with Quality Control teams to enhance methodologies, troubleshoot issues, conduct root cause analyses, and oversee method validation and lifecycle management.
  • Assist the Product Development team in creating assays to assess process and product characteristics.
  • Engage in testing of clinical manufacturing materials, provide method training and transfer, analyze data, troubleshoot challenges, and conduct thorough reviews.
  • Participate in technology transfer initiatives with both internal and external collaborators.
  • Meticulously execute and document laboratory procedures and experiments, ensuring comprehensive record-keeping through Electronic Lab Notebooks (ELN).

Required Qualifications:

  • Background in cell therapy, immunology, or a related discipline; PhD with 0-2+ years of experience (MS with 4+ years or BS with 6+ years considered); prior experience in the industry is preferred.
  • Desirable experience in cell and gene therapy within an Analytical Development capacity.
  • Technical proficiency in flow cytometry and cell sorting; familiarity with antigen density quantification, phospho-flow, or co-culture assays is advantageous.
  • Experience in the development and qualification of flow-based methodologies.
  • Proficient in MS Word, Excel, PowerPoint, and scientific data analysis tools such as GraphPad Prism and NovoExpress/FCS Express.
  • Capability to thrive in a dynamic and fast-paced work environment.

*Comprehensive job description available upon request.*